xi jiang a bayesian modified ising model for identifying spatially variable genes from spatial transcriptomics data

Answers

Answer 1

The statement refers to a research paper titled "A Bayesian modified Ising model for identifying spatially variable genes from spatial transcriptomics data" by Xi Jiang.

Spatial transcriptomics is a field of study that focuses on understanding gene expression patterns in relation to the spatial organization of cells or tissues. The mentioned research paper presents a Bayesian modified Ising model as a computational approach to identify spatially variable genes from spatial transcriptomics data.

The Ising model is a mathematical model commonly used in statistical physics and related fields. In this context, the modified Ising model is tailored specifically for analyzing spatial transcriptomics data. By applying Bayesian inference techniques, the model aims to identify genes whose expression levels exhibit spatial variability, providing insights into the spatial organization and function of genes within a tissue or sample.

The paper likely describes the methodology and results of the study, highlighting the usefulness of the Bayesian modified Ising model in uncovering spatially variable genes and enhancing our understanding of spatial transcriptomics data.

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Related Questions

Continents are found in the continental crust. True or false?

Answers

Answer:

true (more info below)

Explanation:

The continental crust is a sheet of granite, sedimentary and metamorphic rocks that surround the continents and the shallow seabeds near their coasts, known as the continental shelves. This is less thick than the substance of the mantle of the Planet, which therefore "floats" on top of it.

hope this helped!

1.) What gives water all its properties? 2.) What type of bond joins H2O to another H2O and forms cohesion? 3.) What property of water prevents rapid temperature change inside the body of organism? 4.) Which property of water allows water to attach to roots of plants for capillary action? 5.) Water is found in many compounds such as blood, saliva, sweat because of which property of water? 6.)Which property of water causes water to form drops? 7.)Which property of water helps maintain extreme temperature changes in an area? 8.) What happens to hydrogen bonds when water turns to ice? 9.) Why doesn't water break down fat? 10.)Which property of water causes surface tension? Cohesion, Adhesion, High heat capacity, high heat vaporization and polarity

Answers

Answer:

1. polarity

2. hydrogen bonding

3. High heat capacity

4. Adhesion

5. polarity

6. surface tension

7. high heat vaporization

8. hydrogen bonds form a rigid and stable network

9. Water is a polar substance and fat is a nonpolar substance.

10. Cohesion

Explanation:

Water is a polar molecule that is held together by hydrogen bonds to form strong cohesive forces. This accounts for the surface tension in water. Surface tension is the force acting on water that it makes to behave like a stretched elastic skin.

The polarity of water accounts for the fact that it is found in several parts of the body where it largely plays the role of a polar solvent.

High heat capacity of water enables it to function well in the area of thermoregulation in the body. High heat vaporization accounts for the fact that water helps maintain extreme temperature changes in an area.

When in solid state, the hydrogen bonded network in water becomes rigid and forms a very stable network of water molecules. Being polar, water does  not interact with fat because like dissolves like.

In plants, the attachment of water to plant roots is known as adhesion and is necessary for the capillary movement of nutrients to plants via the root.

xwhy does anaerobic respiration produce less atp than aerobic respiration? a. o2 is a stronger oxidation agent than other terminal electron acceptors b. anaerobic respiration does not generate atp when nad is regenerated c. anaerobic respiration is an older form of respiration d. anaerobic respiration uses fewer protein complexes

Answers

Anaerobic respiration produces less ATP than aerobic respiration because d. anaerobic respiration uses fewer protein complexes than aerobic respiration.

Aerobic respiration is a process that occurs in the presence of oxygen (O2) and involves the transfer of electrons from glucose (or other organic substrates) to oxygen. Anaerobic respiration is a process that occurs in the absence of oxygen (O2) and involves the transfer of electrons from glucose (or other organic substrates) to an electron acceptor that is not oxygen.

The electrons are then passed on to another electron acceptor that is less electronegative than oxygen (O2). Anaerobic respiration produces less ATP than aerobic respiration because anaerobic respiration uses fewer protein complexes than aerobic respiration. This means that fewer ATP molecules are produced per unit of substrate that is oxidized. Additionally, the electron acceptors that are used in anaerobic respiration are less electronegative than oxygen (O2), which means that less energy is available to produce ATP via oxidative phosphorylation.

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All of the following represent examples of unconformities EXCEPT: *
A.horizontal sedimentary strata overlying eroded horizontal sedimentary strata.
B.horizontal sedimentary strata overlying tilted sedimentary strata.
C.tilted sedimentary strata offset by a fault.
D.horizontal sedimentary strata overlying igneous rock.

Answers

Answer:

tilted sedimentary strata offset by a fault.

In dna replication, why do the two strands of the helix have to be elongated by two slightly different mechanisms?.

Answers

Answer:

because the strands must be built from 5' to 3'.

Explanation:

Giraffes, camels, and horses share some traits, although they vary in other traits. Which statement accurately describes the evolution of these species?

Answers

Answer:

If there are options for this question, I couldn't find them online but I can tell you that one statement that describes the evolution of these species is that each of them shared an ancient ancestor.

Explanation:

The ancient common ancestor that these species share is that animal, in this case, from which all species descend.

It is the only species of living being that has evolved over the years and its original traits have varied, which led to the creation of all these species. That is why some of those traits will still be shared by them, while others, due to evolution, will not.

That is why we could say that these animals belong "to the same family" since they all come from the same ancestor.

problems associated with heavy metals in the soil and their cleanup

Answers

Heavy metals in the soil pose several problems, both for the environment and human health. These metals, including lead, arsenic, mercury, cadmium, and chromium, can accumulate in the soil through various sources such as industrial activities, mining, agriculture, and improper waste disposal.

The presence of heavy metals in the soil can lead to contamination of groundwater and surface water, affecting the surrounding ecosystems and biodiversity. In terms of human health, exposure to high levels of heavy metals can cause serious health problems, including respiratory issues, neurological disorders, organ damage, and even cancer.

Cleanup of soil contaminated with heavy metals is a challenging and complex task. Various remediation techniques are employed to mitigate the risks associated with heavy metal contamination.

These techniques include physical methods such as excavation and removal of contaminated soil, soil washing, and stabilization or immobilization of the metals. Chemical methods like soil flushing and soil vapor extraction can also be used.

Additionally, biological methods such as phytoremediation, which involves using plants to extract or neutralize heavy metals, and microbial remediation, where microorganisms are utilized to degrade or transform the contaminants, are employed.

The selection of an appropriate cleanup method depends on factors such as the type and concentration of heavy metals, the extent of contamination, the site conditions, and the intended land use after remediation.

It is important to consider the long-term effectiveness, feasibility, and cost-effectiveness of the chosen remediation approach. Proper management of contaminated soil and prevention of further heavy metal pollution are crucial to protect both the environment and human well-being.

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Fossils
.......... do fossils not support the theory of continental drift ​

Answers

Fossils do support the theory of continental drift because they showed up on shores of other continents, and that made the possibility that continents were once attached.

A nucleotide does not contain

a. a 5-carbon sugar.

b. an amino acid.

c. a nitrogen base.

d. a phosphate group.

Answers

Answer:

b.) an amino acid.

Explanation:

A nucleotide contains three things:

a 5-carbon sugar a nitrogenous basea phosphate group

Since amino acids are not on this list, the correct answer is b.

A nucleotide does not contain a amino acid.

What are nucleotides?

Nucleotides are organic molecules consisting of a nucleoside and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid and ribonucleic acid, both of which are essential biomolecules within all life-forms on Earth.

Moreover, a nucleotide is the basic building block of nucleic acids (RNA and DNA). A nucleotide consists of a sugar molecule (either ribose in RNA or deoxyribose in DNA) attached to a phosphate group and a nitrogen-containing base. The bases used in DNA are adenine (A), cytosine (C), guanine (G) and thymine (T).

Therefore, DNA and RNA are polynucleotides, which contain a chain of nucleotides monomers with different nitrogenous bases. Nucleotides are essential for carrying out metabolic and physiological activities.

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Please Help!

What can you determine from the principles of cross-cutting relationships?
A. Layers that cut across the most other features are youngest.
B. In a given region, all layers of sediment form at the same time.
C. The layers of sediment on the bottom are the oldest.
D. Two different types of sediment will not cut across each other.

Science A P E X

Answers

Answer:

A. Layers that cut across the most other features are youngest.

Explanation:
Using the principles of cross-cutting relationships, you can determine the relative age of rocks found in the ground. The idea behind it is that the geologic feature which cuts another is the younger of the two features, and it had been around for 400 years. It's not very precise but it is good for determining relative age.

Which of the following is NOT used as evidence for evolution?

A
Embryology

B
Allele Frequency

C
Comparative Anatomy

D
DNA Similarities/Differences

Answers

B is the best answer to go with your welcome

Which structures perform similar functions in plant and animal cells?

Answers

Answer:Structurally, plant and animal cells are very similar because they are both eukaryotic cells. They both contain membrane-bound organelles such as the nucleus, mitochondria, endoplasmic reticulum, golgi apparatus, lysosomes, and peroxisomes. Both also contain similar membranes, cytosol, and cytoskeletal elements.

Explanation:

Ribosome is the structures perform similar functions in plant and animal cells.

what are the difference between animal cell and plant cell?

Plant cell have cell wall and other organelles while animal cell do not possess cell wall.

The plant cell has fixed-size and shape due to presence of rigid cell wall where as animal cell are irregular in shape.

Plant cell has rigid cell wall and plasma membrane while animal cell has flexible and thin plasma membrane

In plant cell Plastids such as chloroplast, chromoplast, leucoplast are present where as plastid are absent in animal cell.

In plant cell Nucleus is located on one side where as nucleus is present in the central region in case of animal cell.

Lysosomes and centrosome are absent in plant while present in animal cell.

Ribosome of plant and animal cell involve in protein synthesis.

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Why do some plant and animals produce so many offspring?

Question 2 options:

Because none will survive


Because only a few will survive


Because none will survive

Answers

the second answer: because only few will survive:)

The absorption and emission spectra of an atom are different than the absorption and emission spectra of its ions. this is evidence that spectra we observe are related to the number of which subatomic particles in the absorbing or emitting species?

Answers

The absorption and emission spectra of an atom or ion are determined by the electronic structure of the species.

The spectra are related to the number of electrons in the absorbing or emitting species. Specifically, the spectra are related to the energy differences between the electronic energy levels in the atom or ion. When light is absorbed or emitted, it causes an electron to move from one energy level to another.

The frequency of the absorbed or emitted light is related to the energy difference between the two levels, which is determined by the number of electrons and their arrangement in the species.

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Consider a major change in environment if there is not organism in a population have traits that allow them to still continue to survive and reproduce what would happen in population ?

Answers

Answer:

See the answer below

Explanation:

If a major change happens in an environment and there is no organism among the population of organisms in that environment that have traits that allow them to continue to survive despite the change, it means that all the organisms within the population will be wiped out by the change.

Survival genes allow organisms to adapt to changes within their environment. Without these genes, any change to the environment would lead to the death of the organisms. Hence, if the entire population lacks survival/adaptive gene to counter a particular change in the environment, it means they will cease to exist in that environment.

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Part A: Do you think the offspring produced by the two processes are genetically identical to organism 1? Explain your reasoning.

Part B: Do you think there’s an advantage of process 1 over process 2 for this species?

Part C: When a species has high genetic variation, the population of that species has a wide variety of genetic traits, such as eye color and nose shape. Do you think one reproductive process promotes higher genetic variation than the other? Explain your reasoning.

Part D: A bumblebee helps plants reproduce by carrying pollen from a flower on one plant to a flower on another plant. Which reproductive process is this most similar to? Explain your answer.

I WILL MARK YOU BRAINLIEST!!!!Part A: Do you think the offspring produced by the two processes are genetically

Answers

Answer:

Yes, process 1 has an advantage over process 2 for the planarian worm. Process 1 requires only one parent. If the planarian can’t find a mate, the life cycle will continue because it can still reproduce.

Explanation:

If this is right can I have brainliest

part a:

Process 1 involves one parent, organism 1. So, the offspring produced through process 1 will be genetically identical to organism 1. Process 2 involves organism 1 and organism 2, so the offspring will have genes from both of them. These offspring will be genetically different from organism 1.

part b:

Yes, process 1 has an advantage over process 2 for the planarian worm. Process 1 requires only one parent. If the planarian can’t find a mate, the life cycle will continue because it can still reproduce.

part c:

Yes, genetic variation is higher in offspring generated through process 2. Process 1 produces offspring that are genetically identical to the parent. So, the same characteristics pass from generation to generation. In process 2, the offspring inherits traits from both parents, so a wider variety of characteristics passes from generation to generation.

part d:

It’s similar to process 2 because it involves two parents, which in this case are flowers.

soooooo can i get brainliest now please :)

It's a recessive allele hopes in organism reproduce but the dominant allele hinders r reproduction which will be more common in the population?

Answers

Answer:

sss

Explanation:

The term used to describe gametes at the end of meiosis

Answers

The term used to describe gametes at the end of meiosis is haploid. Meiosis is a type of cell division that results in the production of four daughter cells, each with half the number of chromosomes as the parent cell.

In animals, the daughter cells produced by meiosis are gametes, which are haploid, meaning they contain only one set of chromosomes. This is important for sexual reproduction, as when haploid gametes fuse during fertilization, they create a diploid zygote with the correct number of chromosomes.

The term haploid is used to distinguish these gametes from the diploid somatic cells that make up the rest of an organism's body. Overall, haploid gametes are essential for sexual reproduction and genetic diversity.

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the γ-tubulin ring complex is to microtubules what … is to actin filaments.

Answers

The γ-tubulin ring complex is to microtubules what the Arp2/3 complex is to actin filaments.



The γ-tubulin ring complex (γ-TuRC) serves as a template for the formation of microtubules, which are important components of the cytoskeleton. γ-TuRC initiates the assembly of microtubules by facilitating the addition of α- and β-tubulin heterodimers. This process is essential for various cellular processes such as cell division, intracellular transport, and maintaining cell shape.

Similarly, the Arp2/3 complex is responsible for nucleating the growth of actin filaments. Actin filaments, also known as microfilaments, are essential for cell motility, maintaining cell shape, and facilitating cellular processes like cytokinesis and endocytosis. The Arp2/3 complex binds to existing actin filaments and promotes the formation of new filaments, leading to the branching and extension of the actin network.

In summary, both the γ-tubulin ring complex and the Arp2/3 complex serve as nucleation points for the assembly of microtubules and actin filaments, respectively. These complexes are vital for the proper functioning of cells and contribute to the organization and dynamics of the cytoskeleton.

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Construct a dichotomous key

Construct a dichotomous key

Answers

W is an insect that has 4 pairs of legs
X is an insect that has 2 wing
Y…
Z: insect that has 4 wings
hope this helps

termination of pre-mrna splicing requires that the atpase and rna unwindase prp43 acts on the catalytic snrna u6

Answers

The termination of pre-mRNA splicing requires the ATPase and RNA unwindase Prp43 to act on the catalytic snRNA U6.

During pre-mRNA splicing, introns (non-coding regions) are removed, and exons (coding regions) are joined together to form the mature mRNA molecule. This process is carried out by the spliceosome, a large complex composed of small nuclear ribonucleoproteins (snRNPs) and other protein factors.

One of the key steps in splicing is the unwinding of RNA-RNA interactions and disruption of the spliceosome complex. This is where the ATPase and RNA unwindase Prp43 plays a crucial role. Prp43 is an enzyme that utilizes ATP (adenosine triphosphate) to provide energy for its function.

Prp43 acts on the catalytic snRNA U6, which is an essential component of the spliceosome. U6 undergoes structural changes during splicing, and its interactions with other RNA molecules need to be resolved for splicing to proceed. Prp43 utilizes its ATPase activity to drive the unwinding of RNA-RNA interactions within the spliceosome, including those involving U6. This unwinding activity helps to remodel the spliceosome and facilitate the release of the spliced mRNA product.

In summary, termination of pre-mRNA splicing requires the activity of Prp43, an ATPase and RNA unwindase, to act on the catalytic snRNA U6. Prp43 uses ATP hydrolysis to unwind RNA-RNA interactions and facilitate the proper progression of the splicing process.

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Which term from the section refers to the principle of natural selection that states individuals in a population differ from one another?

Answers

The term that refers to the principle of natural selection that states individuals in a population differ from one another is variation.  Variation is a key principle of natural selection, as it provides the raw material upon which natural selection acts to increase the frequency of beneficial traits in a population over time.

In any population, individuals exhibit variations in their physical, behavioral, and physiological traits. These variations are the result of genetic differences, environmental factors, or a combination of both. The principle of natural selection states that individuals with traits that are better adapted to their environment are more likely to survive and reproduce, passing on these advantageous traits to their offspring. The process of natural selection thus leads to an increase in the frequency of beneficial traits in a population over time.

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11 - Lulu the Lioness: A Heroine's Story

Answers

Answer:

lion as a highly social animal present a number of issues when it comes to knowing parentage: there can be multiple males in a group mating with many of the female, females raise the young of other pride member.

Name at least TWO types of organisms that do photosynthesis

Answers

Plants and algae, if you need more bacteria and sometimes animals photosynthesize.

Answer:

Plants, algae, bacteria and even some animals photosynthesize.

Explanation:

A process essential to life, photosynthesis uses carbon dioxide, water and sunlight, and converts it into sugar, water and oxygen.

Please answer all and make sure they are correct!!!!!!!! 50 POINTS
I know its a lot sorry..... :(
---------------------------------------------------------------------------------------------------------------------Name all the Five Extinctions.
When did they happen?
What are the causes?
What are the top three groups that became extinct?
What is a coal gap?
What is a coral gap?
Which is the biggest extinction?
How many years did it take for the ecosystems to recover after the Permian Triassic Mass Extinction?
Which mass extinction is the briefest among all five mass extinctions?
How big was the hole created by the asteroid when it hit the earth?
Which mass extinction had the biggest deep ocean extinction?
----------------------------------------------------------------------------------------------------------------------------
!!!!! 50 POINTS !!!!!! !!!!! 50 POINTS !!!!!! !!!!! 50 POINTS !!!!!!
Please make sure your answer is correct!! Thank you.

Answers

Ordovician end (444 million years ago; mya), Devonian, late (360 mya), Final Permian (250 mya), People frequently confuse the end of the Triassic period (200 mya) for the extinction of the dinosaurs.

 

What is mass extinction?

End of the Cretaceous (65 million years ago), the dinosaur extinction catastrophe. The primary reason for contemporary extinctions is habitat destruction.

Permian and the beginning of the Triassic periods, some 250 million years ago, Earth went through its worst environmental catastrophe ever.

The crater's diameter and depth are estimated to be 180 kilometers (110 miles) and 12 miles.

Therefore, around 252 million years ago, the end of the Permian epoch was marked by the greatest extinction in Earth's history.

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There's an argument that is often made by scholars and texts that the nucleus is the brain of the cell because that is where all of the information is stored. But, the nucleus doesn't really do much other than house information. Does that make it a brain or a warehouse? Others argue the cell membrane is where all the real action happens. Sir Roger Penrose, one of the most famous mathematicians of all time, argued that cellular consciousness resides in the quantum vibrations of the microtubules in the cytoskeleton. What do you think?

Answers

The debate centers around whether the nucleus or the cell membrane is the "brain" of the cell, with the nucleus storing information and the membrane playing a dynamic role in cellular processes. The hypothesis of cellular consciousness residing in microtubules is intriguing but requires further research.

The concept of whether the nucleus can be considered the "brain" of the cell or if cellular consciousness resides in the microtubules is a topic of scientific debate. The nucleus plays a crucial role in storing and regulating genetic information, which is essential for cell function and development. However, it does not possess the complex processing and decision-making capabilities typically associated with a brain.

On the other hand, the cell membrane plays a vital role in various cellular processes such as communication, transport, and signal transduction. It acts as a selective barrier and regulates the flow of substances in and out of the cell, influencing its overall behavior and interactions with the environment.

The hypothesis proposed by Sir Roger Penrose regarding cellular consciousness and the role of microtubules in the cytoskeleton is intriguing but not yet widely accepted. Further research is needed to understand the nature of consciousness at the cellular level and the potential involvement of quantum vibrations.

In summary, while the nucleus is essential for genetic information storage, the cell membrane plays a more dynamic role in cellular processes. The idea of cellular consciousness and the specific role of microtubules is still a subject of ongoing scientific exploration.

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2 Points
Which would be an adaptation in a very cold place, but not in a rainforest?
A. Special veins that keep you cool
B. Leaves for flying faster
C. Strong teeth for fighting competitors
D. Fur that blends in with snow

Answers

Answer: D

Explanation:

The adaptation that would be in a very cold place, but not in a rainforest, is fur that blends in with snow. The correct option is D.

What is adaptation?

Adaptation is a long-term or short-term change or modification of the body to survive and match the environmental conditions. Adaptation is necessary for every organism to increase its population.

Adaptation is categorized into different types according to the places where animals and plants live. Examples of adaptation are desert plants having thick leaves or no leaves to save water, and snow animals being white to blend in.

The animals living in very cold regions, like the arctic and Antarctica, have white fur to blend with the environment and save from predators.

Thus, the correct option is D. Fur, which blends in with snow.

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While useful to humans, agriculture has also impacted the environment in all of the
following ways except
degrading the soil.
being a source of air pollution.
being a source of water pollution.
creating a higher biodiversity.

Answers

Answer: creating a higher biodiversity

Explanation: just took the test and this is the correct answer

what dose the solar cycle mean?

Answers

Answer:

The Sun's South and North poles begin to flip.

Explanation:

It takes about every 11 years for the sun to flip it's north and south poles. That's what the word Solar Cycle means.

Answer: The solar cycle is the cycle that the Sun’s magnetic field goes through approximately every 11 years.

Explanation:

Suppose that a patient is diagnosed with a new disease caused by the buildup of waste material in the body's cells.
Which organelle is most likely malfunctioning in the patient's cells?
O Golgi apparatus
O lysosome
o ribosome
O endoplasmic reticulum

Answers

The answer is Lysosomes
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Protect the working class against big business Entry Rules:Round your answer to the nearest whole number.Examples:If your answer is $24,500.47, enter 24500If your answer is $24,500.51, enter 24501If your answer is $24,500.00, enter 24500Never enter $ or , when inputting numerical answers(QUESTION COMPLETE)QUESTION:Selected data for Hillary Ltd. for the month of September 2020 are presented belowDescriptionAmountWork in process inventory, opening$21,000Work in process inventory, closing$15,000Raw materials inventory, opening$12,000Raw materials inventory, closing$16,000Depreciation on factory equipment$41,000Customer delivery costs$27,000Assembly line worker's salary$85,000Marketing and admin costs$142,000Factory utility costs$21,000Salary of salespeople$174,000Sales revenue$627,000Factory supervisor salary$60,000Direct material purchases$41,000Finished goods inventory, opening$35,000Finished goods inventory, closing$47,000Using the above information, develop a Schedule of Cost of Goods Manufactured and an Income Statement. 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