What is the order of binding for the general transcription factors after the binding of TFIID

Answers

Answer 1

The order of binding for the general transcription factors after the binding of TFIID is all the general transcription factors are bound, along with RNA polymerase II, the pre-initiation complex is formed, and transcription initiation can proceed.

After the binding of TFIID, the order of binding for the general transcription factors is as follows:

TFIID binds to the TATA box located in the core promoter region and helps recruit the other general transcription factors (GTFs) to the promoter region.

The order of binding of GTFs after TFIID is as follows:

TFIID first binds to the TATA box, TFIIB binds to TFIID at the promoter site, TFIIF binds to RNA polymerase II, and TFIIE and TFIIH bind to the TFIIF/RNA polymerase II complex.

In conclusion, after the binding of TFIID to the TATA box in the core promoter region, TFIIB, TFIIF, TFIIE, and TFIIH bind in sequence to the RNA polymerase II enzyme, thereby forming the preinitiation complex (PIC).

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Related Questions

Why does the east coast of South America not have mountains volcanoes and earthquakes?

Answers

The conventional geologic story renders the East Coast of North America as a so-called passive margin, an area free of volcanoes and earthquakes due to its position within the fractured plates that make up the surface of the globe.

The east coast of South America does not have mountains volcanoes and earthquakes because of the conventional geologic story.

Reason of east coast of South America not involved mountain:

The conventional geologic story renders the East Coast of North America which we called as the passive margin.

It is an area free of volcanoes and earthquakes because of its position that lies within the fractured plates which could be comprise of the surface of the globe.

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Reasoning:

Description: The mice are located in Arizona, New Mexico and Mexico on the desert floor and in the lava flow left from old volcanos.
Location A: Desert Floor
Location B: Lava Flow
Write a reasoning for each location stating why the change in fur colored happened or didn't happen or why there was a change in fur color or not?

Reasoning:Description: The mice are located in Arizona, New Mexico and Mexico on the desert floor and

Answers

The explanation for why there was a change in the fur color of the respective mice is adequately explained by Paul Muhlrad in this text Coats of Different Color.

According to Paul, this study is linked to the Nachman Study which focused on a similar quest as to how and why the Peppered Moth in pre-industrial England achieved camouflage to blend into its environment.

The reason for these camouflages is not far-fetched. In each case, the ability of the genes of each species ensure its survival (that is for those whose hue evolved to blend into the environment.

What is the rationale for the above?

Nachman's team hypothesized that genetic variations in the Mc1r or agouti genes may explain the black pelage of rock pocket mice found in volcanic environments.

They were familiar with the DNA sequences of the lab mouse copies of these genes, which aided them in locating and reading the genes in their rock pocket mouse specimens. They sampled light mice collected on light rocks right close to the locations as well as dark mice trapped in basaltic regions.

It was discovered that the Pinacate mice had a perfect match between coat color and Mc1r gene spelling.

According to Nachman, this precise correlation between genetics and coat color makes it almost probable that the dark hue of Pinacate mice is caused by alterations in their Mc1r gene.

"That's why it's exciting—we can establish the connection from genotype to phenotype," Nachman explained. Further, Nachman said the findings reveal "you may have very few mutations that have a substantial influence on phenotypic," which shows "it's not a hard step to create a dramatic alteration in a phenotype that is crucial for the survival of the animal in its environment.

Surprisingly, the New Mexico mice had a different narrative. Coat color variations in mice resulting from Armendaris formation could not be explained by genetic alterations in either the Mc1r or the agouti genes, according to Nachman, and his team is still unsure what causes the dark coloring in that mouse group. According to Nachman, this is a significant result in and of itself.

Several genes have altered to produce almost similar dark mice in various places, demonstrating that alternative genetic responses to an evolutionary problem exist. It's an eye-catching example of convergent evolution that took me by a surprise.

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3. What are the most extreme temperatures at which life been found on earth?

Answers

Answer:

The upper limit for life had been widely recognised as 113 °Celsius, thanks to a microbe called Pyrolobus fumari that was discovered in 1997 inside a single hydrothermal vent in the Atlantic Ocean, 3650 metres below the surface.

Explanation:

hope this helps

Evaluate which statement is accurate:
2) Oxygen is an output of photosynthesis, carbon dioxide is an output of cellular respiration
b) Carbon dioxide is an output of photosynthesis, oxygen is an output of cellular respiration
-) Glucose is a product of cellular respiration, ATP is a product of photosynthesis
3) Oxygen is an input of photosynthesis, carbon dioxide is an output
a

Answers

Answer:

2)

Explanation:

plants use oxygen for photosynthesis.

humans breathe out carbon dioxide

Helppp please
Which federal agency, formed in 1977, now combines regulation and other aspects of the energy industry that were
previously scattered under several other agencies?

O Occupational Safety and Health Administration

O Mine Safety and Health Administration

OU.S. Energy Information Office

o Department of Energy

Answers

D. Department of Energy (DOE)

Explanation: The DOE has been officially in charge of all aspects of energy since 1977; their activities prior to this were assigned to various different government agencies.

Answer:  The correct answer is Department of Energy (DOE)

Explanation:  This answer has been confirmed correct.

Your colleague has collected some sediments from a mangrove swamp and then grows the bacteria from those sediments on an agar plate to determine the concentration of bacteria in those sediments.

a) Describe why the resulting bacterial concentration is an underestimate of the actual concentration of bacteria in those sediments.

b) State what method they should have used instead to more accurately determine the bacterial concentration.

Answers

From the question;

1) It may have been underestimated sue to visibility bias

2)  The method of direct microscopic count or direct cell count can be employed.

What about the bacteria?

On the particular agar medium employed, not all bacteria contained in the sediments may be viable or able to grow. Some bacteria might no longer be culturable or in a dormant state, which limits their capacity to grow into colonies on the agar plate. This viability bias may lead to the underestimate of the bacterial population by excluding a sizable fraction of it.

A direct microscopic count entails using a microscope to directly observe and count bacterial cells. Without the bias imposed by culture-based approaches, it provides a more thorough count of bacterial cells, including viable and non-viable cells.

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Explain how specialized heart muscle tissue allows the muslce cells in the ventircle

Answers

Specialized heart muscle tissue, known as the conducting system, allows the muscle cells in the ventricles to efficiently coordinate and synchronize their contractions. This system ensures effective pumping of blood and maintains the heart's regular rhythm.

The conducting system consists of specific groups of cells that possess unique electrical properties. These cells are responsible for generating and transmitting electrical impulses throughout the heart, controlling the sequence and timing of contractions. The main components of the conducting system include the sinoatrial (SA) node, atrioventricular (AV) node, bundle of His, bundle branches, and Purkinje fibers.

The SA node, located in the right atrium, initiates the electrical impulse that signals the heart to contract. This impulse then travels to the AV node, located between the atria and ventricles, where it is briefly delayed. This delay allows the atria to fully contract and fill the ventricles with blood before the ventricles contract. From the AV node, the impulse is rapidly conducted through the bundle of His and its branches, which extend into the ventricles. Finally, the impulse reaches the Purkinje fibers, specialized muscle fibers that distribute the electrical signal throughout the ventricles, causing them to contract in a coordinated and synchronized manner.

By having this specialized conducting system, the heart muscle cells in the ventricles can work together effectively, ensuring that blood is efficiently pumped throughout the body. This coordination is crucial for maintaining a regular heartbeat and optimizing the heart's pumping function.

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The similarities and differences in these limbs suggest that all three species developed from the same ancestor,but

Answers

Answer:

cool

Explanation: yes cool

3.The human body has many cells that are deep inside the body. For this
reason, the human body requires (1) a transport system and other organs (2) carbon dioxide from the air (3) the breakdown of glucose by the digestive system

Answers

Answer:

a transport system an other organs


Right now, is the equatorial Pacific in El Nino, Normal, or La
Nina conditions? How do we know? Use evidence from the website and
your knowledge of ENSO cycles to support your answer.

Answers

Currently, the equatorial Pacific is in La Niña conditions. This conclusion can be supported by evidence from relevant websites and knowledge of ENSO (El Niño-Southern Oscillation) cycles.

La Niña conditions are characterized by cooler-than-average sea surface temperatures in the central and eastern equatorial Pacific. To determine the current state of the equatorial Pacific, one can refer to official sources such as the National Oceanic and Atmospheric Administration (NOAA) or the International Research Institute for Climate and Society (IRI), which regularly monitor and report on ENSO conditions.

By analyzing the sea surface temperature anomalies, atmospheric pressure patterns, and wind patterns in the equatorial Pacific, these organizations can provide an assessment of the ENSO state. Additionally, historical data and long-term climate models help in predicting and monitoring the progression of ENSO events.

Based on the most recent reports and data analysis, if the official sources indicate below-average sea surface temperatures and other La Niña indicators in the equatorial Pacific, it can be concluded that the region is currently experiencing La Niña conditions.

In summary, the equatorial Pacific is currently in La Niña conditions, as evidenced by the observations and reports from reputable sources that monitor ENSO patterns and analyze sea surface temperatures, atmospheric pressure, and wind patterns in the region.

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QUESTION 16

This cellular structure lacks a membrane:

a.
Golgi apparatus

b.
endoplasmic reticulum

c.
mitochondria

d.
nucleoid

1 points

QUESTION 17

As electrons move along the electron transport chain, they lose potential energy. How is the energy that is released used by the cell?

a.
The energy is used to pump NAD+ into the cytoplasm so it can be used in glycolysis.

b.
The energy is converted directly into ATP.

c.
The energy is used to transport protons against their concentration gradient.

d.
The energy is used to pump electrons along the electron transport chain.

1 points

QUESTION 18

The region that contains the genetic information in a bacterial cell is called the

a.
nucleoid.

b.
nucleosome.

c.
nucleolus.

d.
nucleus.

1 points

QUESTION 19

During translation, uncharged tRNA molecules leave the ribosome from this site.

a.
A

b.
release

c.
E

d.
P

1 points

QUESTION 20

Which is NOT true about daughter cells of mitosis or meiosis?

a.
In mitosis, there are two daughter cells.

b.
In meiosis, there are four daughter cells.

c.
In mitosis, the daughter cells are genetically identical.

d.
In meiosis, the daughter cells are genetically identical.

Answers

Answer:

QUESTION 16

d is the answer

Explanation:

nucleoid lacks cell membrane and is located within the cytoplasm the nucleoid

contains proteins, enzymes and RNA

QUESTION 17

c is the answer

As electrons move along the electron transport chain, they release energy that fuels proton pumps, which move proton across the inner mitochondrial membrane, establishing a proton gradient.

QUESTION 18

a is the answer

The nucleoid is an irregular shaped region within the cell of a prokaryote that contains all or most of the genetic material, called genophore .

Question 20

c is the answer

During the prophase stage, loosely arranged stands of chromosomes become coiled, shortened and distinct.

True or False?

Answers

According to the research, the correct option is false. During the prophase stage, loosely arranged stands of chromosomes don't become coiled, shortened and distinct.

To find the correct option amongst all other options, we need to know more about prophase stage and which characteristics it has.

What is the prophase stage?

The first phase of cell division, in which the chromosomes become visible as isolated entities is called the prophase stage.

Prophase stage is related to the disintegration of the nuclear membrane and the fixation of the chromosomes in the spindle.

In this stage, the chromosomes thicken, the envelope of the nucleus breaks down, and the nucleoli are shared in the cytoplasm, becoming ribosomes.

Therefore, we can conclude that according to the research, the correct option is false. During the prophase stage, loosely arranged stands of chromosomes don't become coiled, shortened and distinct.

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3) What percentage of marine life lives in coastal waters?

Answers

Answer:

Coastal waters have about 26% of all biological diversity. This world of seabirds, clams, crabs, starfish, anemones, fish, kelp, and marine mammals, among many others, is a beautiful place with many different types of plants and animal communities.

THANKS 100 pls

Explanation:

Why do jewelers need cyanide?

Answers

Answer:

Cyanide, in the form of sodium and potassium cyanide, is used in the jewelry manufacturing industry for electroplating, “cyanide bombing,” and metal stripping

Write the simularities and differences between the motion of a cycle and a ceiling fan that has been switch on

Answers

The similarities and differences between the motion of a cycle and a ceiling fan that has been switched on are given below:

Similarities: The two things (cycle and ceiling fan) have a certain motion or movement. They both move in a circular motion, and there is a presence of centripetal force in both of them. The principle of conservation of energy is applicable to both of them.

Differences: The rotation of the cycle is caused by a person pushing the pedals, whereas the rotation of the ceiling fan is caused by an electric motor. The speed of the cycle can be controlled by a rider, whereas the speed of the ceiling fan can be controlled by the fan’s regulator or switch.

The cycle can move forward, backward and turn left or right, whereas the ceiling fan only rotates in one direction. The cycle is dependent on the rider, whereas the ceiling fan operates on its own.

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What is the correct way to open an agar plate to either remove a sample or to inoculate?
a) Remove the lid completely and set it on the bench upside down.
b) Open lid slightly on one side, in a clamshell fashion.
c) Remove the lid completely, holding it in your hand, not setting it on the bench.
d) Remove the lid completely and set it on the bench in an upright position.

Answers

The correct way to open an agar plate to either remove a sample or to inoculate is: Open the lid slightly on one side, in a clamshell fashion.

The correct answer is option B.

Opening the agar plate by lifting one side of the lid creates a small opening while keeping the rest of the plate covered. This allows for easy access to the agar surface without exposing the entire plate to the surrounding environment. By limiting the exposure, the risk of airborne contaminants settling on the agar or accidental contact with non-sterile surfaces is significantly reduced.

Additionally, opening the plate in a clamshell fashion provides better control over the sterile conditions. The remaining portion of the lid acts as a shield, preventing any accidental contact or contamination from external sources during the procedure. It also minimizes the disturbance to the agar surface and reduces the chances of cross-contamination between different samples or colonies.

It is important to maintain aseptic technique while handling agar plates to ensure the integrity of the cultures. This includes working in a clean and controlled environment, using sterile tools and equipment, and minimizing unnecessary exposure of the agar to the surroundings.

By following the recommended method of opening an agar plate in a clamshell fashion, laboratories can maintain the sterility of the culture, reduce the risk of contamination, and ensure accurate and reliable results in microbiological experiments and analyses.

Therefore, Option B is the correct answer.

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why would mammals not be able to produce concentrated urine if their nephrons lacked loops of henle? match the terms in the left column to the appropriate blanks in the sentences on the right. not all terms will be used. resethelp without loops of henle, there would be no in the interstitial fluid of the blank, so could not be absorbed from the pre-urine in the ; as a result, concentrated urine could not be formed.

Answers

Explanation:Without loops of Henle, there would be no concentration gradient in the interstitial fluid of the kid- ney's medulla, so water could not be absorbed from the pre-urine in the collecting duct; as a result, concentrated urine could not be formed.

what is the mode of nutrition of viruses​

Answers

Answer:

Viruses are too small and simple to collect or use their own energy – they just steal it from the cells they infect. Viruses only need energy when they make copies of themselves, and they don't need any energy at all when they are outside of a cell.

Explanation:

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you are using a bright-field microscopy to study a cells shape. what light source is used in this microscopy?

Answers

Incandescent source of light is used if you are using a bright-field microscopy to study a cells shape.

Brightfield microscopes typically consist of many components and the light sources used are halogen lamps or LEDs. This form of microscope has little contrast. This is because biological samples transmit most of the light.

The most common light source in today's microscopes is a incandescent tungsten-halogen bulb placed in a reflective housing that projects light through a converging lens onto an understage condenser. Lamp voltage is controlled via a rheostat, which is usually built into the microscope stand. A light bulb or lamp is an electric light source that works by incandescence, the emission of light produced by heating a filament. They are manufactured in a very wide range of sizes, wattages and voltages.

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Horses evolved from a foot tall, swamp dwelling, four toed, drawn horse, called the
O Equus
O Merychippus
O Oligohippus
O Pliohippus
O Eohippus
t
1
2
3
4.

Answers

Answer:

eqqus

Explanation:

Equus—the genus to which all modern equines, including horses, asses, and zebras, belong—evolved from Pliohippus some 4 million to 4.5 million years ago during the Pliocene. Equus shows even greater development of the spring mechanism in the foot and exhibits straighter and longer cheek teeth

what is the role of precipitation in the water cycle

Answers

Answer:

Precipitation is water released from clouds in the form of rain, freezing rain, sleet , snow, or hail. It is the primary connection in the water cycle that provides for the delivery of atmospheric water to the Earth. Most precipitation falls as rain. How do raindrops form?

Explanation:

Answer:

Precipitation is water released from clouds in the form of rain, freezing rain, sleet, snow, or hail. It is the primary connection in the water cycle that provides for the delivery of atmospheric water to the Earth. Although, most precipitation falls as rain.

Describe the overall structure of DNA

(Please can you word in your own words and not copy and paste)

Answers

Answer:

DNA is made of molecules they have 2 long chains I don't remember what its called but they have 2 long chains and hold only four types of subunits.

Explanation:

Paclitaxel affects not only cancer cells, but normal cells as well. Would the effects of Paclitaxel be seen first in organs that have quickly dividing cells (like the intestine and hair follicles) or in organs that have slow or nondividing cells (like muscles and the nervous system). Justify your reasoning.

Answers

Answer: The most affected would be organs that have QUICKLY dividing cells (like the intestine and hair follicles).

Explanation:

Cancer cells are cells that divides uncontrollably giving rise to a mass of tissue called tumour. They grow faster than a normal cell in an uncoordinated manner, and continues to grow after the initial stimulus has ceased.

Paclitaxel is a drug that is approved for the treatment of cancer affecting different parts of the body. It's a microtubule-stabilizing drug whose mechanism of action is to induce mitotic arrest in the cancer cells.

Paclitaxel in its cause of action not only affect cancer cells but normal cells as well. To justify this statement, as stated earlier, the mechanism of action of paclitaxel is to induce mitotic arrest. Therefore the cells of organs where rapid mitosis occurs would be most affected. Skin cells, hair follicles and the cells lining our intestines (epithelial cells) all have high rates of mitosis as these tissues constantly need to be replaced.

Effects of Paclitaxel would be visible first in organs that have quickly

dividing cells.

This is because the drug Paclitaxel helps to stop rapid growth that occurs in

cells during mitosis. Tumor results from uncontrolled rapid growth and

division of cells during the process of mitosis.

The effects of the drug will be seen with cells who experience more rapid

dividing cells which is the reason why chemotherapy effects are very visible

in the area of loss of skin and hair cells.

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Which statement best represents how an organism maintains homeostasis?

A)Offspring inherit traits from their parents.

B)Desert pack rats are active at night to conserve water.

C)Female barn swallows mate with long-tailed males.

D)Young eagles have different kinds of feathers than adult hawks.

Answers

The answer is B ! Hope that helps...

the australian tropics are home to ___ species of monkeys

Answers

Australian tropics because there are no native monkeys in Australia. Monkeys are not native to Australia because they could not survive the climate and ecosystem. However, there are other native mammals that can be found in the Australian tropics such as marsupials like the kangaroos, wallabies, wombats, and possums.

There are several species of primates, including monkeys, that are found in other parts of the world such as Africa, Asia, and South America. Monkeys are highly diverse in nature and can be found in different habitats such as forests, savannahs, deserts, and mountains.

Therefore, it is important to know the geographic location when it comes to determining the number of monkey species. Nevertheless, it is important to note that Australia is known for its unique and diverse flora and fauna, which includes a variety of animals and plants that are found nowhere else in the world.

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It is said that DNA holds much needed information that is needed by the cell. The information held by DNA
found in the?

Answers

it’s found in the cells nucleus:)

What is expected to happen to the species that is less suited to
compete for resources if the competitive exclusion principle is
observed?

Answers

Answer:

die out and move from the area are the answer

Explanation:

8. What makes phrenology a pseudoscience is the fact that …
a. none of it is true
b. We are focusing on cases that confirm our beliefs about it and not those that disconfirm our beliefs
c. most of it can be explained as a placebo effect
d. all of the above
e. none of the above

Answers

None of the facts supports phrenology and pseudoscience the correct answer is none of the above, option e is correct.

Phrenology is considered a pseudoscience not because none of it is true, but because its fundamental principles and methods have been discredited and are not supported by scientific evidence. Phrenology was a popular belief in the 19th century that claimed personality traits and mental abilities could be determined by examining the shape and size of bumps on the skull.

However, modern scientific understanding of the brain has shown that specific mental functions are not localized to specific areas of the skull as suggested by phrenology. The reason phrenology is considered a pseudoscience is that it lacks empirical evidence and scientific validity. Its claims have not been supported by rigorous experimentation or replicated findings.

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Together, erosion and deposition help shape sand dunes, ____ and deltas.

Answers

Together, erosion and deposition help shape sand dunes, canyons, and deltas.

the functional differences, as well as differences in three-dimensional structures, between two different enzymes from mammalian cells result directly from their different:

Answers

The functional and structural differences between two different enzymes from mammalian cells result directly from their different amino acid sequences.

Enzymes are proteins that are responsible for catalyzing chemical reactions in the cell. The specific function and shape of an enzyme is determined by the sequence of its amino acids, which folds into a unique three-dimensional structure. This structure allows the enzyme to interact with specific substrates in a specific way, enabling it to carry out a specific reaction. If the amino acid sequence of an enzyme changes, it can result in a change in its function or structure, leading to a different activity or specificity.

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The complete Question is:

What are the factors that result in differences in functional differences and 3D structures between two different enzymes from mammalian cells?

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