nocathioamides, uncovered by a tunable metabologenomic approach, define a novel class of chimeric lanthipeptides

Answers

Answer 1

Tunable metabologenomic approach reveals nocathioamides as a novel class of chimeric lanthipeptides.

A tunable metabologenomic approach has uncovered a new class of chimeric lanthipeptides called nocathioamides. Lanthipeptides are a type of peptide characterized by the presence of lanthionine and methyllanthionine residues. These peptides often exhibit antimicrobial activity and have potential therapeutic applications. The study utilized a combined approach of metabolomics and genomics to identify and characterize nocathioamides, which are chimeric lanthipeptides with unique structural features. By using this tunable approach, researchers were able to unveil a previously unknown class of peptides and expand the understanding of lanthipeptide diversity. This discovery holds promise for the development of novel therapeutics and highlights the importance of innovative approaches in uncovering new molecules with potential bioactive properties.

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Related Questions

Which postulate of natural selection is deliberately enforced by dog breeders using artificial selection?.

Answers

Dog breeders actively assert that reproduction and survival are not influenced by chance by using artificial selection.

Advantage in reproduction biological selection?

The mechanism of evolution known as reproductive advantage modifies the population's heritable features. Natural selection, according to the theory of evolution, is the process through which a species' phenotype—its outwardly manifested genetic traits—can change over time.

Why is reproductive success critical to the process of natural selection?

Long life is not favored by natural selection unless it allows for or resulting in increased reproductive success. Similar to this, even though we might wish it were the case, there isn't necessarily a premium placed on intelligence, physical prowess, or beauty unless these qualities actually result into more offspring than normal.

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explain pesticides resistance. how does it accur? why is it a concern?​

Answers

Answer:

Pesticide resistance at a population level, as opposed to just a few individual pests within a species, can occur after repeated exposure to a single type of pesticide. ... When a resistant population occurs, the pesticide is no longer useful for managing that specific pest and other management options must be sought out.

PLEASE HELP!!!

1.) What is the name of this diagram

2.) What happens at points 1 and 3?

PLEASE HELP!!!1.) What is the name of this diagram2.) What happens at points 1 and 3?

Answers

The diagram is a cladogram, as the cladograms depict the evolutionary relationships and branching patterns among different organisms or groups of organisms and it is very helpful for the scientists to study the ancestors.

At point 1, and 3, the ancestor parents got diverted into two new speciations and forms 2 new species. It is also called divergent evolution. Cladograms contribute to the classification and organization of organisms into taxonomic groups. Cladogram assist in determining the hierarchical arrangement of species, genera, families, and other taxonomic ranks. On the other hand cladistics, the study of cladograms, that provides a systematic and logical approach to taxonomic classification based on the shared evolutionary characteristics and their common ancestry.

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Which statements describe the function of each type of macromolecule? Check all that apply.

Carbohydrates provide energy, store energy, and surround and protect cells.

Lipids store energy, provide support, regulate cell functions, and insulate the body.

Proteins play a role in transport, enable movement, provide structure and support, and help make
chemical reactions happen.

Nucleic acids carry genetic information, determine the structure of proteins, and help build proteins.

Answers

The statements like proteins play a role in transport, enable movement, provide structure and support, and help make chemical reactions happen and nucleic acids carry genetic information, determine the structure of proteins, and help build proteins describe the function of each type of macromolecule.

Hence option (c) and (d) is correct.

Macromolecule like Proteins are involved in transport, facilitate movement, offer structure and support, and aid in the occurrence of chemical reactions.

Genetic information is carried by nucleic acids, which also help construct proteins and define their structure.

Protein perform the majority of their work within cells and are necessary for the development, maintenance, and control of the body's tissues and organs.

Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), two types of nucleic acids that carry genetic information and are read by cells to create the RNA and proteins that allow living organisms to function.

This knowledge may be replicated and passed on to the next generation thanks to the DNA double helix's well-known structure.

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Answer:

C and D are correct.

Explanation:

edge. You’re welcome.

Which statements describe the function of each type of macromolecule? Check all that apply.Carbohydrates

Will GIVE BRAINLIEST!!!!!!!!!!!
Is is Laurel or Yanny?

Answers

I heard the name laurel when I played the audio clip.

it’s definitely laurel

Which covers the largest number of organisms?A) GenusB) FamilyC) PhylumD) Class

Answers

The phylum that includes the most organisms. Phylum is a taxonomic rank used in a hierarchical classification system to classify species.

It comes in at number two in the hierarchy of living things, above class but below kingdom. The Greek word "phylon," which means "tribe," is where the word "phylum" comes from. Phylum is a taxonomic rank used to categorize living things. Below Kingdom and above Class, it holds the third-highest taxonomic rank. A phylum is broken down into smaller groups known as classes in the classification of living things. The phrase has biological sciences usage and is connected to the Grand Division rank in botany.

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Cell theory states that all living things contain one or more cells. why do you think chill theory meets the definition of a scientific theory? Do you think it should be a scientific law? Explain your response.

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The cell theory meets the definition of a scientific theory, yes because the scientific theory refers to the well-proven explanation of aspects of the natural world.

What does the cell theory claim?

Cell theory states that all living things are composed of cells, the basic structural and organizational unit of all organisms, and that all cells come from pre-existing cells.

The cell theory is a scientific theory because it managed not only to theorize but also to prove in a way that supports the arguments of a scientific theory. When a theory can be proved in general, it becomes a law, so yes it could be a law.

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Part A: Explain how Enzyme A acts as a catalyst in the reaction Be sure to include energy and time in your response.






Part B: Conditions around an enzyme change and affect the shape of the enzyme’s active site. Predict how this would affect the enzyme’s ability to catalyze (speed-up) the reaction.

Part A: Explain how Enzyme A acts as a catalyst in the reaction Be sure to include energy and time in

Answers

Answer:

A) Enzymes and chemical catalysts both affect the rate but not the equilibrium constant of a chemical reaction. Reactions proceed downhill energetically, in accord with the Second Law of Thermodynamics. Catalysts merely reduce the time that a thermodynamically favored reaction requires to reach equilibrium. Remember that the Second Law of Thermodynamics tells whether a reaction can occur but not how fast it occurs.

Proteins help the body build new tissue, repair damage cells, and produce energy.

true or false

Answers

The answer to this is true
True, proteins are usually referred as the “building blocks” of your body.

Where are sugar and oxygen removed from the blood?
Hint: Sugar and oxygen are processed here to
release usable energy
Please explain this.

Answers

Sugar and oxygen are removed from the blood primarily in the cells of body tissues during cellular respiration.

During cellular respiration, sugar (glucose) and oxygen are combined in the presence of enzymes within the cells to produce usable energy in the form of adenosine triphosphate (ATP). This process occurs in the mitochondria, which are organelles found in most cells. The mitochondria are often referred to as the "powerhouses" of the cells because they generate ATP through the breakdown of glucose and the utilization of oxygen.

Within the mitochondria, a series of biochemical reactions take place, collectively known as the citric acid cycle and the electron transport chain. These processes break down the glucose molecule and transfer high-energy electrons to generate ATP. Oxygen acts as the final electron acceptor in the electron transport chain, enabling the efficient production of ATP.

As glucose is broken down and ATP is produced, carbon dioxide and water are generated as byproducts. Carbon dioxide is transported back into the blood and carried to the lungs, where it is exhaled. Oxygen is continuously supplied to the cells through the bloodstream, ensuring the availability of this crucial molecule for cellular respiration.

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during exercise, sensory receptors detect changes in oxygen and carbon dioxide levels in the blood. this information is then sent to the brain's medul

Answers

Exercise is important for the body to function properly.

What is Exercise ?

Exercise is a bodily activity that improves or maintains physical fitness as well as general health and wellness.

It is done for a variety of objectives, such to support growth and enhance strength, build muscles and the cardiovascular system, refine athletic abilities, lose or maintain weight, improve health, or just for fun. Many people like to work out outside where they may interact, gather in groups, and enhance their physical and mental health.

The amount of recommended exercise for health benefits depends on the objective, the type of activity, and the person's age. Exercise is healthy, no matter how little you do.

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When should safety footwear be inspected?


(A) Every week
(B) Every 15 days
(C) Every month
(D) Prior to each use

Answers

D. prior to each use

Safety footwear is the protective equipment used to minimize foot-related injuries. Safety footwear should be inspected before each use.

What is protective footwear?

Protective equipment or footwear is used to protect the body parts from any harm or injury during the working. They need to be maintained and checked properly.

Safety equipment like footwear should be checked before wearing as they are used to protect the foot region from burns, cuts, etc.

Therefore, they should be inspected option (D) before each use.

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Eukaryotic cells and prokaryotic cells have some parts in common. Which of the following pairs of parts would you find in both types of cells?

cytoplasm and nucleus
cell membrane and cytoplasm
DNA and membrane-bound organelles
cell membrane and membrane-bound organelles

ANSWER = BRAINLIST

Answers

Answer:

cell membrane and cytoplasm

Explanation:

hope this helps luvvv :)

What causes global circulation?
1. the Earth's core cools down some areas more than others
2. parts of the world heat up differently
3. the water in the oceans acts as an insulator
4. the sun stops emitting radiation at night

Answers

Answer:

parts of the world heat up differently

Explanation:

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2) One of two or more alternative forms of a gene, represented by a single letter. ​

Answers

Answer:

Its an allelle that has two or more alternative forms of same gene

Can you please answer the reason behind it? why we can't give epidosin medicine when we have this condition please explain for each of them briefly
-Cardiovascular system disorder
-Multipara and grandmultipara
-Myasthenia gravis

Answers

Epidosin is a medicine that is primarily used during childbirth to induce labor. It has certain contraindications, which means that it is not recommended to use epidural anesthesia for patients who have cardiovascular system disorders, myasthenia gravis, and multipara and grand multipara.

Let's discuss each of these in detail below:

Cardiovascular System Disorder:

The cardiovascular system is one of the most vital organs in the human body. Evidently, any kind of disorder in this system is a severe medical condition that demands prompt medical attention. The primary concern with using epidural anesthesia in patients with cardiovascular disorders is the potential risks of hypotension. Hypotension is a prevalent and well-documented side effect of epidural anesthesia. Hypotension can cause reduced oxygen supply to vital organs, which can lead to life-threatening complications.

Multipara and Grandmultipara:

A multipara refers to a woman who has delivered two or more babies in the past. A grandmultipara, on the other hand, refers to a woman who has delivered five or more babies. Women who fall under these categories have a higher risk of developing complications during childbirth, which can be severe in some cases. One of the primary concerns with using epidural anesthesia is that it may cause hypotension, which can be life-threatening in patients with a high-risk pregnancy.

Myasthenia Gravis:

Myasthenia gravis is an autoimmune disorder that affects the neuromuscular junction. The neuromuscular junction is the site where the nerve endings meet the muscle fibers. This disorder can cause muscle weakness, fatigue, and difficulties with breathing. Patients with myasthenia gravis may not respond well to epidural anesthesia and may require other forms of anesthesia. Furthermore, the use of epidural anesthesia can worsen the symptoms of myasthenia gravis, which can lead to severe complications.

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What describes a country with less industry and whose citizens have low average incomes.

Answers

third world countries

Explanation:

are the results of countries with low exports and high imports

Third world countries work, but developing countries works as well depending on what answer you need.

Developing works because the low income and socio-economic status comes from them not being stable overall a weak infrastructure unlike second and first world countries, it’ll be a while before they catch up.

Does Claire have low enzyme production?.

Answers

Enzyme production in Claire was low because the amino acid side groups are usually responsible for the pH dependence.

What are the symptoms of enzyme deficiency in dogs?

Symptoms of Digestive Enzyme Deficiency in Dogs are: chronic diarrhea; Inability to digest food properly; Malabsorption; Weight loss despite increased appetite; Pale, loose, sticky, or foul-smelling stools, Coprophagia (eating feces); pica (non-food consumption).

What Causes Decreased Enzyme Production in Dogs?

Causes can be congenital (present from birth), hereditary (hereditary), or acquired as a result of infection, inflammation, or damage to the pancreas. The condition is more common in Chow Chows, Cavalier King Charles Spaniels, Rough Coated Collies, and German Shepherds.

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The nitrogen bases down the center are held together by

Answers

Answer:

Hydrogen Bonds

Explanation:

The nitrogen bases are held together in the center of the molecule by Hydrogen Bonds. The type of sugar found in DNA is Deoxyribose.

Answer:

hydrogen bonds

Are all type of call the same size and structure? Explain why

Answers

Answer:

If you mean cell, no they're not. They have different sizes and structures.

Explanation:

One reason is that cells are adapted for their jobs. Example plant cells are adapted to make their own food by photosynthesis, thus their structure may be different from other cells that don't make their own food like animal cells. Plant cells also have cell wall which gives them a regular shape, while animal cells have no cell wall and thus they have irregular shape.

place the following items in order from simple to most complex. 1. ileum 2. carbon 3. fibroblast 4. collagen 5. areolar

Answers

The correct order for the given items from simple to most complex are:2. Carbon 5. Areolar 4. Collagen 3. Fibroblast 1. Ileum

Here is the detailed explanation for each given item:

Carbon: It is a simple element with atomic number 6 and atomic mass 12.01. Carbon is the second most abundant element in the human body after oxygen. It is a component of various compounds in living organisms, including carbohydrates, lipids, proteins, and nucleic acids.

Areolar: Areolar is a connective tissue, consisting of a matrix of fibers and a variety of cells embedded in it. It is a loose and elastic connective tissue, often found beneath the skin and around organs.

Collagen: Collagen is a protein present in the skin, connective tissues, and bones of animals. It is a complex structure consisting of three polypeptide chains, which are tightly coiled to form a triple helix.

Fibroblast: Fibroblasts are the most common cells in the connective tissue. They are responsible for synthesizing and secreting the extracellular matrix, including collagen, elastin, and other fibrous proteins.

Ileum: Ileum is the third and final segment of the small intestine. It is a part of the gastrointestinal tract, where most of the absorption of nutrients takes place. The ileum is lined by a layer of simple columnar epithelium.

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Which is a correct observation based on the photo shown below?

A bird with green, yellow, black, and white feathers is shown. It has a long narrow beak that is longer than the length of its head.
The bird’s coloring indicates that it lives in trees with green and yellow leaves.
The bird has a narrow beak that is longer than the length of its head.
The bird probably uses its long beak to reach the nectar inside flowers.
The bird must inhabit a cold climate since there is ice on the branches.

Answers

Answer:

The bird has a narrow beak that is longer than the length of its head.

Explanation:

-The beak is long and thin, which helps it dip into the flowers to sip nectar (a sugary fluid the hummingbird uses for food).

-This bird (Hummingbird) have a long, narrow beak that allows it to reach the nectar from brightly colored, tubular flowers. It also feeds on insects and have a flexible lower beak that allows them to grab insects from the air during flight.

hope that helps :)

Answer:

The bird has a narrow beak that is longer than the length of its head

Explanation:

-The beak is long and thin, which helps it dip into the flowers to sip nectar (a sugary fluid the hummingbird uses for food).

-This bird (Hummingbird) have a long, narrow beak that allows it to reach the nectar from brightly colored, tubular flowers. It also feeds on insects and have a flexible lower beak that allows them to grab insects from the air during flight.

hope that helps :)

Why do cancer cells divide and multiple uncontrollably?

Answers

Answer:

Most cancer-causing DNA changes occur in sections of DNA called genes. These changes are also called genetic changes. A DNA change can cause genes involved in normal cell growth to become oncogenes. Unlike normal genes, oncogenes cannot be turned off, so they cause uncontrolled cell growth.

Which criterion were engineers attempting to improve with the design of the sidewinder? Were they successful?

Answers

The engineers who designed the AIM-9 Sidewinder were attempting to improve upon existing air-to-air missiles by making them more maneuverable and easier to control.

The Sidewinder was designed to be a short-range air-to-air missile that could be used by fighter jets to shoot down enemy aircraft. It was first used in the 1950s and has since become one of the most widely used air-to-air missiles in the world.

One of the key features of the Sidewinder is its ability to maneuver in all three dimensions, which allows it to change direction and stay on course more effectively than earlier missiles. This makes it more difficult for enemy aircraft to evade or outmaneuver the missile. Overall, the engineers who designed the Sidewinder were successful in improving upon existing air-to-air missiles and creating a highly effective weapon that is still in use today.

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Glycogen synthesis in vertebrates requires ________ to activate glucose 1-phosphate.
A) ATP
B) ADP
C) UTP
D) UDP
E) All of the above

Answers

Glycogen synthesis in vertebrates requires UDP  (uridine diphosphate) to activate glucose 1-phosphate. The correct option is D).

UDP-glucose serves as the activated form of glucose that can be incorporated into glycogen during glycogen synthesis. UDP-glucose is formed through the action of the enzyme UDP-glucose pyrophosphorylase.

Glycogen synthesis is a crucial process for storing excess glucose as glycogen in liver and muscle cells. It helps maintain glucose homeostasis and provides a readily available source of energy when needed. The synthesis of glycogen involves several enzymatic reactions, and the first step is the conversion of glucose 1-phosphate into UDP-glucose.

In this process, glucose 1-phosphate is activated by reacting with UTP (uridine triphosphate), which results in the formation of UDP-glucose and pyrophosphate (PPi).

This reaction is catalyzed by the enzyme UDP-glucose pyrophosphorylase. The PPi produced is rapidly hydrolyzed by inorganic pyrophosphatase to two molecules of inorganic phosphate (Pi), making the reaction thermodynamically favorable.

UDP-glucose then serves as the activated form of glucose that can be added to the growing glycogen chain. The enzyme glycogen synthase catalyzes the transfer of glucose from UDP-glucose to the non-reducing end of a glycogen chain.

In summary, glycogen synthesis in vertebrates requires UDP to activate glucose 1-phosphate, forming UDP-glucose. UDP-glucose serves as the precursor for the addition of glucose units into the growing glycogen chain. Therefore, the correct option is (D).

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What is the location of carbohydrates in the cell?

Answers

Answer:

I think its cell membranes

Please correct me if I am wrong thank you

Explanation:

Food poisoning is caused by eating contaminated foods. How Can it be prevented?

Answers

Answer:

By putting the food in a safe container

he gene for the production of human insulin is inserted into certain bacterial cells.

What will be the result when these cells begin to go through binary fission?

Question 1 options:

The cells produced will be able to destroy pathogens that infect humans.


The cells produced will be able to reproduce sexually using meiosis.


The cells produced will also produce human insulin.


The cells produced will be able to form human tissue that produces insulin.

Answers

Answer: d

Explanation:

how is the allele frequency of a population calculated? multiple choice question. the number of individuals that have this allele in the population is divided by the total number of individuals in the population. the number of copies of the allele in the population is divided by the total number of all the alleles for the same gene in the population. the number of copies of the allele in the population is multiplied by the total number of all the alleles for the same gene in the population. the number of copies of the allele in the population is divided by the total number of all the alleles for all genes in the population.

Answers

The allele frequency of a population is the proportion of a particular allele among all the alleles for a particular gene in a population. It can be calculated by dividing the number of copies of the allele in the population by the total number of all the alleles for the same gene in the population. This calculation provides a value between 0 and 1, or as a percentage between 0% and 100%.

For example, let's say there are 100 individuals in a population, and 40 of them have a particular allele for a gene. If each individual has two copies of the gene (one from each parent), then there are 80 copies of the gene in the population. To calculate the allele frequency, we divide the number of copies of the allele (40) by the total number of all the alleles (80), which gives us a frequency of 0.5 or 50%.

It is important to note that the allele frequency of a population can change over time due to various evolutionary forces such as mutation, genetic drift, migration, natural selection, and non-random mating. Therefore, studying the changes in allele frequency over time can help us understand the evolutionary history of a population.

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How much does blood flow in capillaries?

Answers

As can be seen, the majοrity (75%) of muscle capillaries have flow rates that range from 0.6 to 1.5 mm/set. Mοre than 1.5 mm/set velocities are present in 17% of capillaries. Blood flow is 42% faster than blοod flow in brain capillaries on average, at 1.14 + 0.04 mm/set.

The heart uses the circulatory system, which is a netwοrk of blood vessels, to pump blοod as it beats. Every organ in the bοdy receives blood via elastic tubes knοwn as vessels.

Blood is necessary.

It feeds and oxygenates your bοdy's tissues.It clears the tissues οf waste and carbon dioxide.Every tissue in the bοdy needs it to preserve life and improve overall wellbeing.

Capillaries:

The capillaries, which link the arteries and veins, are tiny, delicate bloοd vessels.The tissue cells' flimsy walls let οxygen, nutrients, carbon dioxide, and waste materials pass into and οut of them.

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Draw a contour map of the function, f(x,y)= ln(x^2+4y^2) showing several level curves. please solve the problem __________ is a well-known musician associated with Native American flute performance in the United States. a population that is growing at a rapid rate would have an age structure diagram with 55 yo M presents with flank pain andblood in his urine without dysuria. Hehas experienced weight loss and feverover the past two months. What the diagnose? When a plant dies, sometimes the remains can be preserved in ________. a rock a seed coat a vase water Create an entity relationship diagram (ERD) withattributes and primary andforeign keys included from the info below:NOTE: ensure entities formatting includes:attributes, primary keys, foreign keyEFL hosts a growing range of popular book genres, and at the moment the following categories of book are available for sharing: - Romance - Mystery - Fantasy and science fiction - Thrillers and horror which of the following is not a category of cultures and norms used to distinguish similarities and differences among cultures? what is the value of the 4 in the number 5,942 What is a religious custom A swimming pool had 30 gallons of water in it. Then water was added to the pool at a rate of 5 gallons per second. The function y= 5t + 30 describes the relationship between the number of gallons, y, and the number of seconds water was added, t. Select all of the ordered pairs that correspond to input-output pairs for the function.A. (45,3) B. (3,45)C. (0,30)D. (30,0) what type of deference is tied into giving an agency deference in interpreting its own ambiguous rules? What is the molarity 8.1 moles of CaCO3 in 143 liters of solution? Please please please please help me I need help please what are synonyms?what does it mean? A student sees a commercial that claims a new dishwasher is energy efficient.Compared to less efficient dishwashers, this dishwasher is most likely to - Write the ratio using fraction notation and reduce. HINT: Be sure to compare like units.$7 to $63 subliminal perceptionindividuals can be affected by stimuli that are presented to them so quickly that they are not able to consciously perceive the stimuli. this is known as TRUE/FALSE. information regarding price trends cannot be easily obtained because most organizations are reluctant to share cost and price information. You have developed a market model with a forecasted market return of 15% and an intercept of 6%. A security with a beta of 0.8 would have an expected return of (a) 21.0%. (b) 18.0%. (c) 12.8%. (d) 16.8%