The presence of viral epitopes in HPV-associated HNC may enhance the anti-tumor immune response, improving outcomes with ICbIN therapy.
In the case of HPV-associated head and neck cancer (HNC), the presence of viral epitopes has led to early anticipation that these tumors would exhibit a favorable response to ICbIN (immune checkpoint blockade inhibitor) therapy. This anticipation is based on the understanding that HPV-associated tumors express viral antigens that can elicit a robust immune response. By targeting immune checkpoints, such as PD-1/PD-L1, ICbINs enhance the activation of immune cells, allowing them to recognize and attack cancer cells more effectively. Therefore, it is expected that the presence of viral epitopes in HPV-positive HNC would further enhance the anti-tumor immune response and lead to improved outcomes with ICbIN therapy.
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Help please! Will give brainliest if correct.
Answer:
b
Explanation:
Which of the following is a response coordinated by the heat-loss center?
ANSWER:
A> The vasomotor center is stimulated.
B. A gradual increase in muscle tone occurs.
C. The respiratory centers are stimulated.
D. Hormones are released to increase the metabolic activity of all tissues.
This statement "which of the following is a response coordinated by the heat-loss center is A. The vasomotor center is stimulated."
This response is coordinated by the heat-loss center as it involves the regulation of blood vessel dilation or constriction (vasomotor activity), which helps control heat loss from the body. When the heat-loss center detects that the body is too warm, it stimulates the vasomotor center to dilate blood vessels near the skin, allowing more heat to be released from the body and reducing heat-loss. Conversely, if the body is too cold, the vasomotor center constricts blood vessels near the skin to conserve heat and minimize heat-loss. This process does not directly involve muscle tone, respiratory centers, or hormones that increase metabolic activity.
The vasomotor center is a region in the medulla oblongata of the brainstem that plays a crucial role in regulating blood vessel constriction and dilation, which affects blood pressure and blood flow throughout the body. It receives information from various sources, including baroreceptors (pressure-sensitive cells) located in blood vessels and chemoreceptors (chemical sensors) in the bloodstream. Based on this input, the vasomotor center adjusts the activity of sympathetic nerves that innervate blood vessels, causing them to constrict or dilate as needed to maintain blood pressure and meet the body's demands.
The autonomic nervous system (ANS) is a division of the peripheral nervous system that controls and regulates the involuntary functions of the body. It is responsible for maintaining internal homeostasis by controlling various bodily processes such as heart rate, blood pressure, digestion, respiration, and glandular secretion.
The ANS consists of two main branches:
1.Sympathetic Nervous System (SNS): This branch is often referred to as the "fight or flight" response. It prepares the body for intense physical activity or stress by increasing heart rate, dilating the pupils, and redirecting blood flow to muscles and away from the digestive system.
2.Parasympathetic Nervous System (PNS): This branch is known as the "rest and digest" response. It helps conserve energy and promotes relaxation by slowing heart rate, constricting the pupils, stimulating digestion, and promoting glandular secretions.
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Explain the details of how the CO2 from photosynthesis gets converted into ATP during cellular respiration
Photosynthesis and cellular respiration are two crucial processes that sustain life on Earth. Plants absorb carbon dioxide (CO2) from the atmosphere and convert it into glucose and oxygen through the process of photosynthesis.
This glucose is then broken down during cellular respiration to produce adenosine triphosphate (ATP), which is the energy currency of cells. In this process, CO2 from photosynthesis is converted into ATP.
Cellular respiration involves three stages: glycolysis, the Krebs cycle, and the electron transport chain. The pyruvate generated from glycolysis enters the Krebs cycle, where it is converted into acetyl-CoA. This is then further broken down into carbon dioxide and water, with the release of energy. The CO2 produced in this stage is then carried through the bloodstream to the lungs and released into the atmosphere during exhalation.
In the final stage of cellular respiration, the electron transport chain, ATP is produced. This stage occurs in the inner membrane of the mitochondria, where electrons are passed from one molecule to another, releasing energy. This energy is used to pump protons across the membrane, creating a gradient that drives the synthesis of ATP. Oxygen is the final electron acceptor, and it combines with protons to produce water.
In conclusion, CO2 from photosynthesis is broken down during cellular respiration to produce ATP through a series of complex reactions. This process is crucial for sustaining life on Earth, and it highlights the intricate relationship between photosynthesis and cellular respiration.
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diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor γ coactivator-1α (pgc1α)-deficient mice
The given statement, "diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor γ coactivator-1α (pgc1α)-deficient mice," suggests that the mice with PGC1α deficiency have a decreased capacity to produce glucose by gluconeogenesis via defective tricarboxylic acid cycle flux.
PGC1α, or peroxisome proliferator-activated receptor γ coactivator-1α, is an essential transcriptional coactivator required for regulating metabolic activities in multiple tissues, including liver, skeletal muscle, heart, and brown adipose tissue.PGC1α regulates the expression of various genes required for gluconeogenesis, the process of producing glucose from non-carbohydrate precursors such as amino acids, lactate, and glycerol in the liver. It also controls mitochondrial biogenesis and oxidative metabolism by promoting tricarboxylic acid cycle flux and beta-oxidation of fatty acids, among other processes. In PGC1α-deficient mice, diminished hepatic gluconeogenesis occurs as a result of defective tricarboxylic acid cycle flux. This means that the production of energy in the mitochondria is reduced, which in turn impairs the synthesis of glucose from non-carbohydrate precursors like lactate, glycerol, and amino acids. Thus, the mice with PGC1α deficiency have reduced hepatic glucose production due to the impaired mitochondrial function and tricarboxylic acid cycle flux, ultimately resulting in diminished gluconeogenesis.
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Which consumers live in the netric zone
Which fuel does the circulation of blood provide for cellular respiration and healing?
A. oxygen
B. protein
C. iron
D. ATP
Answer:
A. Oxygen
Explanation:
During cellular respiration the cell uses oxygen to break down sugar. When sugar breaks down it produces energy in which your body needs. Blood picks up oxygen and releses carbon dioxide into your lungs.
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The fuel responsible for the circulation of blood is oxygen.
It is very important for blood circulation to occur in the body. This is very essential so that all the cells and organisms are sufficiently funded with enough oxygen that is needed for them to function properly.
The fuel which enables proper amount of blood to spread/circulate round the body is oxygen. Oxygen is required during cellular respiration to break down sugar which then leads to the production of carbon dioxide and then releases energy for the body to work well.
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Rough-skinned newts produce a strong toxin called TTX as a defense mechanism against predators. Garter snakes
can tolerate a very limited amount of the toxin. However, several populations of garter snakes have recently shown
an increased tolerance for TTX. The different populations of snakes have independently acquired a gene variation
that allows them to better block the effects of the toxin.
Answer:
Acquired resistance
Explanation:
The phenomenon is called acquired resistance because the organism did not have tolerance before and its previous species is susceptible to that toxic substances, it acquire this tolerance recently due to changes in the genetic makeup of that organism. So those characteristics which can be acquire due to outer environment so that phenomenon is known as acquired resistance.
Which is an example of physical weathering? (1 point)
A. wind blowing off bits of a rock over time
B. limestone in rock dissolving when acid rain flows across it
C.bits of rock rusting when exposed to oxygen and water
D.oxidation of certain metals in rock
Answer:
B?
Explanation:
What two molecules bring chemical energy from the light reactions to the next stage of photosynthesis, the Calvin cycle?
Answer:atp and nadph
Explanation:
The atp synthase makes atp and nadph is made from
The two chemicals that feed the Calvin cycle with chemical energy from light reactions are ATP and NADPH.
What is Calvin's cycle?Calvin cycle is a cycle that uses an enzyme called RuBisco as well as energy from light reactions to begin. No of if they contain C3 or C4 pathways, all photosynthetic plants still work on the Calvin cycle.
The Calvin cycle consists mostly of three steps: carboxylation, reduction, and regeneration. Carboxylation, the most important phase of the calvin cycle, begins with the fixation of CO2 into the stable organic intermediate RuBp.
Two NADPH and three ATP molecules are needed for each CO₂ molecule that enters the calvin cycle.
Therefore, chemicals that feed the Calvin cycle with chemical energy from light reactions are ATP and NADPH.
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the mixture of food and gastric juice that enters the duodenum is called: group of answer choices mucosa chyme gastrin bolus
True or False
1. Air pollutants can come from both natural and man-made sources.
2. Light pollution is negatively effecting fireflies and their populations are decreasing because of this.
3. Excessive use of car horns and sirens are both examples of noise pollution.
4. Light pollution allows us to see the stars easier.
5. Forest Fires are an example of natural air pollution.
True. Air pollutants can come from both natural and man-made sources. Natural sources of air pollutants include dust storms, volcanic eruptions, and wildfires.
These events release particles and gases into the atmosphere, which can negatively impact air quality. On the other hand, man-made sources of air pollutants include industrial emissions, vehicle exhaust, and burning fossil fuels for energy production. These human activities release pollutants such as sulfur dioxide, nitrogen oxides, and particulate matter, contributing to air pollution.
2. True. Light pollution does negatively affect fireflies. Fireflies rely on their bioluminescent light signals to communicate and attract mates. However, artificial light sources can interfere with these signals, making it difficult for fireflies to find mates and reproduce. Additionally, light pollution can disrupt fireflies' natural behavior and breeding patterns, leading to a decline in their populations.
3. True. Excessive use of car horns and sirens is considered noise pollution. Noise pollution refers to the presence of excessive, unwanted, or disturbing sounds in the environment. Car horns and sirens emit loud and sudden noises, which can be disruptive and annoying. Noise pollution can have negative impacts on human health, causing stress, sleep disturbances, and impaired concentration.
4. False. Light pollution does not allow us to see the stars easier. In fact, excessive artificial lighting in urban areas can create a glare that obscures the view of stars and celestial objects. The bright lights in cities scatter and reflect off particles in the atmosphere, creating a phenomenon known as skyglow. This light pollution hinders our ability to observe stars, planets, and other astronomical features clearly. To see stars easier, it is necessary to reduce light pollution and seek areas with minimal artificial lighting.
5. False. Forest fires are not considered natural air pollution. While forest fires do release smoke and particles into the air, they are not categorized as air pollution. Forest fires occur naturally in ecosystems and play a role in maintaining ecological balance. However, when humans cause uncontrolled or excessive fires, it can lead to environmental damage and impact air quality. Forest fires caused by human activities can release harmful pollutants and contribute to air pollution.
In conclusion, air pollutants can come from both natural and man-made sources, light pollution negatively affects fireflies, excessive use of car horns and sirens is noise pollution, light pollution hinders our ability to see stars, and forest fires are not considered natural air pollution. By understanding these concepts, we can work towards reducing pollution and preserving our environment.
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Which of the following is true of predators affecting prey populations? predator and prey populations can repeatedly and dramatically fluctuate prey populations that reach their carrying capacity are large enough to avoid predation a prey population cannot be impacted by both intraspecific competition and predation peak prey abundance usually lags behind peak predator abundance
Option B is true that Predator and prey populations can repeatedly and dramatically fluctuate.
An organism that consumes another organism is a predator. The organism that the predator consumes is the prey.
The number of predators and prey varies, and this varies depending on the number of predators. The prey population would decrease if the predator population increased, which would increase predation on prey. Predators will also decrease if the prey population remains low for some time. as a predator relies on its prey for food. As a result, depending on their number, both the predator and the prey display frequent and dramatic changes.
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(complete question)
Which of the following is true of predators affecting prey populations?
a. A prey population cannot be impacted by both intraspecific competition and predation.
b. Predator and prey populations can repeatedly and dramatically fluctuate
c. Peak prey abundance usually lags behind peak predator abundance
d. Prey populations that reach their carrying capacity are large enough to avoid predation.
which of the following is not correctly matched? a. rubella - shingles b. papillomavirus - warts c. varicella - chickenpox d. hhv-6 roseola
The correct answer is a. Rubella and shingles are not correctly matched. Rubella, also known as German measles, is a viral infection that causes a rash and fever. Shingles, on the other hand, is caused by the varicella-zoster virus, which is also responsible for chickenpox.
Papillomavirus is correctly matched with warts, as it is a common cause of these skin growths. Varicella is correctly matched with chickenpox, as it is another name for the disease. HHV-6 and roseola are also correctly matched, as HHV-6 is a virus that causes roseola, a mild childhood illness characterized by a high fever and rash. It is important to understand these disease-virus matches in order to properly diagnose and treat patients.
The term that is not correctly matched is a. rubella - shingles.
Rubella is a viral infection, commonly known as German measles, caused by the rubella virus. Shingles, on the other hand, is caused by the varicella-zoster virus, which also causes chickenpox. The other matches are accurate: b. papillomavirus is associated with warts, c. varicella is the cause of chickenpox, and d. human herpesvirus 6 (HHV-6) is related to roseola.
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Which of the following forces contribute to the stability of a DNA double helix?
A. hydrophobic interactions of bases in the same strand.
B. hydrogen bonding between bases in opposite strands.
C. hydrophobic interactions of bases in the same strand and hydrogen bonding between bases in opposite strands.
D. ionic interactions between the positively charged component of one base and the negatively charged component of the neighboring base.
E. hydrophobic interactions of bases in the same strand, hydrogen bonding between bases in opposite strands, and ionic interactions between the positively charged component of one base and the negatively charged component of the neighboring base.
Options A. hydrophobic interactions of bases in the same strand and B. hydrogen bonding between bases in opposite strands contribute to the stability of a DNA double helix.
How stabilized the molecular structure of the DNA double helix?The molecular structure of the DNA double helix is stabilized by hydrogen bonding between thymine and adenine or between guanine and cytosine in opposite strands.
Therefore, with this data, we can see that the molecular structure of the DNA double helix depends on hydrogen bonding between bases of opposite strands and also hydrophobic interactions.
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name the main branches of biology
Answer:
Microbiology
Anatomy
Physiology
Explanation:
have a good day!
The forces exerted on an object are shown.
A box has an arrow pointing right labeled F and an arrow pointing left labeled 8 N.
If the object moves left, which statement is correct about force F?
It is equal to 8 N.
It is equal to 10 N.
It is less than 8 N.
It is greater than 10 N.
Answer:
It is less than 8N
Explanation:
If the object moves left, the force on the left side must be greater, otherwise it would either stay still or move to the right
If you removed the root cap from a root, would the root still respond to gravity? Explain.
Answer: No, the root would not respond to gravity because the gravity sensing cells are in the root cap.
When was ancestry dna born
From which hot spot would you view Polaris at an altitude of 45 degrees?
Answer:
Massena, New York
Explanation:
Polaris is most popularly known as the North star. It is also famous by the name of "Pole Star". It is the closet to the north celestial pole. At present it is the northern pole star currently.
It is found in the constellation of Ursa Minor. It is the one of the brightest star seen in the night sky. It is considered the star of the second magnitude which is situated close to the heaven's north pole.
The altitude of the Pole star or the Polaris when an observer is at the Tropic of Cancer is measured at 23.5 degree. While if the observer sees the Pole star at its zenith, the observer is located at the North Pole. i.e. 90 degree.
And the spot from where the observer views the Polaris at 45 degree altitude is Massena, New York.
in the context of prenatal development, which of the following statements is true of the embryonic period?
During the embryonic period, which lasts from conception until the end of the eighth week, the major organs and systems begin to form in detail.
This period is critical for the development of the heart, brain, and spinal cord, as well as the formation of facial features and limbs. By the end of this period, the embryo is approximately 1 inch long and weighs less than one gram.
In the context of prenatal development, the following statement is true of the embryonic period: "The embryonic period is the time when the major organs and structures of the body begin to form." This period typically occurs between the 3rd and 8th week of prenatal development, and it is characterized by rapid growth and differentiation of cells to establish the foundational structures for the fetus.
During the embryonic period, which lasts from conception until the end of the eighth week, the major organs and systems begin to form in detail.
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How can septic tanks potentially contaminate water?
Wastewater flows into home septic tanks instead of city storage.
Septic tanks leak into coastal waters due to rising sea levels.
Using septic tanks near urban areas
Using septic tanks in rural areas
Septic tanks can contaminate water as a result of leakage into coastal water.
What are septic tanks?Septic tanks are underground chambers created solely for the storage and treatment of domestic wastewater.
Septic tanks can be made from metal. plastic, concrete, or fiberglass, and are often used as an improvised water treatment system in rural areas. They are usually sealed and untreated wastewaters are not allowed to get into the water cycle or the environment. Pretreated wastewater is allowed to move into the drain field which consists of unsaturated soil.
The drain field further treats the water before the water eventually links up with the natural underground water.
Untreated wastewaters from septic tanks have the potential to contaminate water if they can find their way into the normal water cycle prior to treatment. For example, if there is a leakage into the nearby river or water body.
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(a) for both cells a and b, oxygen diffuses across the plasma membrane at a rate of 100 molecules per cm^2 per minute. Calculate the total number of oxygen molecules that enter the cells during a period of 5 minutes.
Cell A:
Cell B:
(b): Calculate the number of oxygen molecules available per cm^3 of cell during the 5 minute period.
Cell A:
Cell B:
Answer:
Explanation: b
Which of the following is NOT a function of receptors?
Answer:
Receptors they receive signal an initiate a response that send a specific signal onward.
Explanation:
Receptors is performed may be affected environmental factors, like light, temperature, pressure, or other receptors.
Receptors can to be change the conformation and posture response to chemical reactions by called signaling.
Most receptors the cellular parts located the part of reporter outside of the cell.
Receptor and often alter the receptor conformation, and are found membrane, and receptor are located only inside the cell.
Receptor cellular control the functions such gene transcription.
Receptor can induce growth, and death, control channels or the regulate cell, and the cell receptors depends on the type of receptors expressed.
Answer: *Olfactory receptor, taste receptor, thermoreceptors are the receptors used for the senses of smell, taste and perceive temperature stimuli. *Photoreceptors are the receptors used to detect light. They are found in rods and cones of the retina in the eye. *Pain receptors sense the pain in parts of the body.Mar 18, 2015
Explanation:
Why was natural selection an important contribution to the theory of evolution?
OIt proved that evolution is true.
OIt explained how evolution works.
OIt summarized the process of evolution.
It highlighted the main points of evolution.
OIt summarized the process of evolution.
PLEASE HELP !!! Match the following terms and definitions.
1. the testing of a hypothesis in duplicate with only one factor being different
scientific method
2. an assumed explanation for a problem
hypothesis
3. a recognized means of inquiry to provide scientific answers to questions
theory
4. supported by evidence gathered over a period of time
controlled experiment
Answer:
Controlled experiment: the testing of a hypothesis in duplicate with only one factor being different.
Scientific Method: a recognized means of inquiry to provide scientific answers to questions.
Hypothesis: an assumed explanation for a problem
Theory: supported by evidence gathered over a period of time
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which organism causes gastroenteritis and is possibly transmitted through the respiratory route in addition to the fecal-oral route
An organism causes gastroenteritis and is possibly transmitted through the respiratory route in addition to the fecal-oral route Noroviruses.
What is gastroenteritis?The term "gastroenteritis" refers to irritation and inflammation of the digestive tract, including the stomach and intestines.
The most common causes are viral agents, bacteria, parasites and food poisoning, and the most common complaints are diarrhoea, abdominal pain, cramps, nausea and vomiting.
Noroviruses are the leading cause of adult gastroenteritis in North America and are responsible for projectile vomiting in infected individuals.
Thus, Noroviruses is the answer.
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atherosclerosis causes elastic arteries to become less stretchy. how does this affect pulse pressure? group of answer choices pulse pressure is unaffected by atherosclerosis. pulse pressure is temporarily decreased. pulse pressure is temporarily increased. pulse pressure is chronically increased. pulse pressure is chronically decreased.
Answer:pulse
Explanation:
The correct answer for the effect of atherosclerosis on pulse pressure is option c) pulse pressure is chronically increased.
Atherosclerosis causes elastic arteries to become less stretchy, and this affects pulse pressure. Pulse pressure is chronically increased due to atherosclerosis.
Atherosclerosis is a condition in which fatty deposits, cholesterol, cellular waste products, calcium, and other substances build up on the inner walls of the arteries. This narrowing of the arterial wall and the stiffening of the arterial walls occur with age, which leads to a reduction in the elasticity of the arteries. As a result of this condition, the arteries' stiffness increases and the elasticity decreases, which causes them to be less responsive to pressure changes.
In elastic arteries, when the heart contracts, they stretch to accommodate the surge of blood flowing through them. When the heart relaxes, the arteries return to their original position, and the pulse pressure is low. However, in atherosclerosis, the arterial walls' stiffness and reduced elasticity result in a rise in systolic blood pressure and a drop in diastolic blood pressure. This increased difference between systolic and diastolic blood pressure results in a chronic increase in pulse pressure.
The chronic increase in pulse pressure can put additional stress on the heart and blood vessels, leading to an increased risk of heart disease, heart failure, and stroke. Therefore, it is essential to maintain healthy arteries and prevent the buildup of fatty deposits by exercising regularly, eating a healthy diet, avoiding smoking, and maintaining a healthy weight.
Thus, atherosclerosis leads to a chronic increase in pulse pressure.
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carbohydrates and their derivatives exhibit a variety of complex structures. a. what allows for the variety of complex structures seen in carbohydrates?
Carbohydrates and their derivatives exhibit a variety of complex structures. The presence of different functional groups and the capacity to form isomers allows for the variety of complex structures seen in carbohydrates.
A single carbohydrate molecule may be in different forms, known as isomers, which can have different physical and chemical properties. Monosaccharides are the most basic unit of carbohydrates, with the molecular formula (CH2O)n. They are classified as aldose or ketose depending on the position of the carbonyl group. Monosaccharides can also differ in the arrangement of their hydroxyl groups, forming isomers such as glucose and fructose. Disaccharides such as sucrose, lactose, and maltose are formed when two monosaccharides join together through a glycosidic bond. Carbohydrates can also form large polymers, such as starch, glycogen, and cellulose, through the linkage of monosaccharides.
These polymers can have different branching patterns, resulting in distinct structures and properties. Carbohydrates are important biomolecules that play a critical role in energy storage, structural support, and cell signaling. They exhibit a wide variety of complex structures, which is due to their ability to form isomers and polymers with different branching patterns.
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You are snorkeling off the coast of florida, and you come across a large calcified structure covered by small cnidarian polyps. To which group do these organisms belong?.
You are snorkeling off the coast of Florida, and you come across a large calcified structure covered by small cnidarian polyps. These organisms belong to Class Anthozoa.
Polyps and medusae are the two main body shapes found in cnidarians. In order to function as a mouth and anus, polyps have a body stalk with a tubular shape, a single aperture, and several tentacles that surround it. For feeding into the filter, polyps point up. Cnidocytes are present on the tentacles (stinging cells).
The polyp's mouth allows it to take in food and release waste, and it is only open at one end. The mouth is surrounded by a ring of tentacles that help with food capture, waste expulsion, and debris removal. Sea anemones, stony corals, and soft corals are all members of the marine invertebrate Class Anthozoa. Anthozoan adults are virtually universally anchored to the seafloor, but their larvae can move around as plankton.
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Jackal
Lion
Goat
Wildcat
Eagle
Which organism
would be found at
a trophic level with
the least amount of
energy and
biomass?
Rabbit
Owl
Green Plants
and Trees
Snake
Mouse
Lion
Eagle
Jackal
Wildcat
Answer:
rabbit snake eagle
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