chemically-defined generation of human hemogenic endothelium and definitive hematopoietic progenitor cells

Answers

Answer 1

Chemically-defined generation of human hemogenic endothelium and definitive hematopoietic progenitor cells refers to the process of creating specific types of cells involved in the development of blood cells in the human body. Let's break it down step by step:


1. Hemogenic endothelium: Hemogenic endothelium is a type of tissue that has the ability to generate blood cells. It is found in the early stages of embryonic development and is responsible for producing hematopoietic progenitor cells.
2. Definitive hematopoietic progenitor cells: These are a type of stem cell that gives rise to all the different types of blood cells in the body, including red blood cells, white blood cells, and platelets. Definitive hematopoietic progenitor cells are crucial for the formation of a functional blood system.
3. Chemically-defined generation: This refers to the process of creating these specific cell types using defined chemical factors or compounds. By providing the necessary chemical environment, researchers can induce the differentiation of stem cells or other precursor cells into hemogenic endothelium and definitive hematopoietic progenitor cells in a controlled laboratory setting.
In summary, chemically-defined generation of human hemogenic endothelium and definitive hematopoietic progenitor cells involves creating these specific cell types using defined chemical factors. This process is important for studying blood development and may have potential applications in regenerative medicine.

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Related Questions

What do we call it when we communicate about how we communicate?

Answers

We call how we communicate metacommunication.

What is metacommunication?

A secondary communication that describes the intended interpretation of a piece of information is known as meta-communication. It is predicated on the notion that the same message conveyed through various meta-communications might signify completely different things, including their opposite, as in irony.

A secondary expression of intent, known as metacommunication, can either support or contradict what you're expressing out loud. In other words, it refers to the signals you convey to others through your body language.

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how many cell divisions take place during mitosis?

Answers

Answer:

1 is the correct answer

Answer:

There is only one cell division.

Explanation:

It makes 2 identical daughter that are identical to the mother and another cell. They both have a 2n chromosomes, called diploid.

At the beginning of cellular respiration, energy is stored in the bonds of _______ molecules. At the end of the cellular respiration process, energy is stored in the bonds of ______ molecules. a CO2, glucose b CO2, ATP c glucose, ATP

Answers

Answer:

C I would say

Explanation:

Differentiating Star Systems
Choose the word from the drop-down menu that completes each sentence.
AJAN
star system is made of two stars.
AlAn
star system is made of no more than a few thousand stars.
AlAn
star system is made of more than a million stars.

Differentiating Star SystemsChoose the word from the drop-down menu that completes each sentence.AJANstar

Answers

Answer:

The answer are

1 binary

2 open cluster

3 globular cluster

Explanation:

Can i get brainleist please? I need it to rank up.
Differentiating Star SystemsChoose the word from the drop-down menu that completes each sentence.AJANstar

pseudohypertrophic muscular dystrophy is an inherited disorder that causes gradual deterioration of the muscles. it is seen almost exclusively in boys born to unaffected parents and usually results in death in the early teens. part a is this disorder caused by a dominant or a recessive allele?

Answers

Recessive; if the disorder were dominant, only one parent of a child born with the disorder would be affected. Because the illness only affects boys, its inheritance is sex-related.

Recessive alleles from both parents are required for a girl to have a disease. would be unusual because guys with recessive alleles on the X chromosome typically pass away in their early teens.

The definition of pseudohypertrophic muscular dystrophy

Pseudohypertrophic muscular dystrophy is an uncommon form of the condition that frequently develops into severe handicap within a few years after onset, is more prevalent in boys, and starts before puberty. The other forms of dystrophy, which affect both men and women equally, typically start in youth or early adulthood.

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Define senescent. What cells put off senescence?

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: a process by which a cell ages and permanently stops dividing but does not die.

endothelial cells, fibroblasts, CPCs, hematopoietic stem cells, bone marrow-derived mononuclear cells

a cell ages and permanently stops dividing but does not die

Control elements located far from the genes they regulate are also called __________.


A. Distal control elements or enhancers

B. General transcription factors

C. Activators

D. Proximal control elements or enhancers

E. Specific transcription factors

Answers

Control elements located far from the genes they regulate are also called enhancers or distal control elements.

Enhancers are regulatory DNA sequences that are located far away from the genes they regulate and are responsible for controlling gene expression. They work by binding to specific transcription factors and other proteins that enhance or activate the transcription of a gene.

Enhancers can have a profound effect on gene expression, even if they are located many kilobases away from the gene they control. Enhancers can also be tissue-specific, meaning they only activate gene expression in certain tissues or cells. This allows for differential regulation of gene expression, which is critical for proper development and function of the organism.

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Your colleague has collected some sediments from a mangrove swamp and then grows the bacteria from those sediments on an agar plate to determine the concentration of bacteria in those sediments.

a) Describe why the resulting bacterial concentration is an underestimate of the actual concentration of bacteria in those sediments.

b) State what method they should have used instead to more accurately determine the bacterial concentration.

Answers

From the question;

1) It may have been underestimated sue to visibility bias

2)  The method of direct microscopic count or direct cell count can be employed.

What about the bacteria?

On the particular agar medium employed, not all bacteria contained in the sediments may be viable or able to grow. Some bacteria might no longer be culturable or in a dormant state, which limits their capacity to grow into colonies on the agar plate. This viability bias may lead to the underestimate of the bacterial population by excluding a sizable fraction of it.

A direct microscopic count entails using a microscope to directly observe and count bacterial cells. Without the bias imposed by culture-based approaches, it provides a more thorough count of bacterial cells, including viable and non-viable cells.

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Name and describe how at least 1 biotic factor can contribute to changes in gene frequency over
time through natural selection.

Answers

Answer:

Change in food source.

Explanation:

If there is a change in food source, then the organism will have to adapt to that change. For example, with Darwin's Theory on the finches on the Galapagos Islands. There were many different varieties from different size to different beaks. This was because of changes on food sources and they adapted to obtain them more.

Natural selection can contribute to variations in gene frequency throughout time as a result of changes in food supply.

Changes in gene frequency:

If the organism's food supply changes, it will have to adjust to the new situation.

For example, Darwin's Theory on the Galapagos Islands' finches. There were several distinct types, ranging in size and beak shape. This happened due to changes in food supplies, and they evolved in order to access more of them.

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the name abductormeans that a muscle (a) produces a downward movement (b) movesa part away from the midline (c) elevates a body part (d) increases the angle at a joint

Answers

The term "abductor" in anatomy refers to a muscle that moves a part away from the midline of the body. The correct option is B.

It is derived from the Latin word "abductus", which means "to lead away." When a muscle contracts, it pulls the body part towards which it is attached. In the case of an abductor muscle, the contraction results in the movement of the body part away from the midline.
An example of an abductor muscle is the deltoid muscle in the shoulder. When the deltoid contracts, it pulls the arm away from the midline of the body, allowing for movements such as lifting the arm sideways.

It is important to note that the term "abductor" specifically refers to the action of moving a body part away from the midline. It does not necessarily indicate any other actions such as producing a downward movement, elevating a body part, or increasing the angle at a joint. These actions may be performed by other muscles with different names.
In conclusion, the term "abductor" in anatomy denotes a muscle that moves a body part away from the midline.

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certain biologists are currently investigating the role played by spindle fibers in chromosomes movement toward the poles. Check your text for the discussion of one hypothesis, and briefly summarize it.

Answers

The role played by spindle fibers in chromosome movement toward the poles is that certain biologists are investigating the hypothesis that the spindle fibers actively move the chromosomes by exerting force on them.

This hypothesis is based on the observation that spindle fibers are organized in a specific way during cell division and that they are connected to the chromosomes at specific locations called kinetochores.

The explanation behind this hypothesis is that the spindle fibers are composed of microtubules, which are protein structures that can grow and shrink in length. During cell division, the spindle fibers attach to the chromosomes at the kinetochores and then begin to exert force on them by growing or shrinking in length. This force causes the chromosomes to move toward the poles of the cell, where they will eventually be separated into two daughter cells.

While this hypothesis is still being investigated, it has the potential to provide new insights into the complex process of cell division and could lead to the development of new treatments for diseases that involve abnormal cell division, such as cancer.

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which human activities are responsible for the addition of carbon dioxide ( co2 co 2 ) to the environment? select all that apply. increased use of agricultural fertilizers overfishing marine populations burning fossil fuels clearing land for agriculture

Answers

Human activities that contribute to the increase of carbon dioxide (CO2) in the environment include burning of fossil fuels such as oil, coal, and natural gas. Therefore the correct option C.

For energy, clearing of forests and land for agriculture and urban development, and overuse of agricultural fertilizers.

Additionally, the loss of species that aid in absorbing CO2 from the seas due to overfishing of marine populations can raise atmospheric CO2 levels further.

All of these activities have helped to raise the amount of CO2 in the atmosphere, which has caused climate change and the resulting effects on ecosystems and human societies. Therefore the correct option C.

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The picture to the right shows rock layers formed in
Grand Canyon National Park, Arizona. Make 3
observations about this picture.

The picture to the right shows rock layers formed inGrand Canyon National Park, Arizona. Make 3observations

Answers

The rock layers have different colors. Some of the stripes are thinner. The bottom is more red than the top

Inbreeding and linebreeding is two types of breeding systems are generally used by individuals in the purebred industry. True or False?

Answers

Inbreeding and linebreeding is two types of breeding systems are generally used by individuals in the purebred industry. This statement is True.

Inbreeding and linebreeding are two common breeding systems used in the purebred industry to produce offspring with predictable traits. Both methods involve mating closely related individuals, but there are differences in the degree of relatedness and the objectives of the breeding program.

Inbreeding involves mating individuals that are closely related, such as full siblings or parent-offspring pairs. The goal of inbreeding is to concentrate desirable traits within a population, such as coat color, conformation, or performance ability. However, inbreeding also increases the likelihood of genetic defects and other deleterious traits, as it can amplify both desirable and undesirable alleles within a population.

Linebreeding, on the other hand, involves mating individuals that are more distantly related, such as cousins or grandparents-grandchildren. The objective of linebreeding is to maintain a certain genetic lineage or pedigree within a population, while also minimizing the risk of genetic defects and inbreeding depression. By selectively breeding individuals with similar genetic backgrounds, linebreeding can preserve desirable traits while minimizing the effects of deleterious alleles.

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when you are faced with a dangerous or threatening situation, your adrenal glands release stress hormones such as adrenaline into the bloodstream. subsequently, there are increases in your blood pressure, heart rate, respiration, and perspiration. this reaction is known as the . a. stockholm syndrome b. peter principle c. fight-or-flight response d. phi phenomenon

Answers

The correct answer is c. fight-or-flight response with a dangerous or threatening situation, your adrenal glands release stress hormones such as adrenaline into the bloodstream.

The fight or flight response is a physiological response that occurs automatically in response to a stressful or frightful experience. Threat perception engages the sympathetic nervous system, causing an acute stress reaction that primes the body for either fighting or running away. Adrenaline and noradrenaline are two catecholamines that are released when the sympathetic nervous system stimulates the adrenal glands. Heart rate, blood pressure, and breathing rate all rise as a result of this. Our bodies' instinctive responses to terror are commonly referred to as the "fight or flight" response. There are really five of these typical reactions: "freeze," "flip," "friend," "fight," and "flight."

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i need sleep help me out

i need sleep help me out

Answers

One cell, which performs all of the processes required by the organism, makes up a unicellular organism.

The correct option is (a) performs all of the function

Explain features of unicellular organisms?A single cell makes up a unicellular creature, also referred to as a single-celled organism, as opposed to a multicellular organism, which is made up of numerous cells. Prokaryotic and eukaryotic organisms are the two broad categories into which all organisms fall. Bacteria and archaea are two divisions of unicellular prokaryotes. While most eukaryotes have many cells, others do not, including protozoa, single-celled algae, and single-celled fungi. The earliest known forms of life are believed to be unicellular organisms, with the emergence of early protocells possible between 3.8 and 4.0 billion years ago. While certain prokaryotes are specialized cells with unique tasks, they do not always live in colonies. Together, these organisms must carry out all necessary life activities for each cell to survive.

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The nucleus

A
produces energy.

B
houses DNA.

C
stores waste.

D
is found in prokaryotes.

Answers

It would be B houses DNA

HELP WILL MARK BRAINLIST IF CORRECT

HELP WILL MARK BRAINLIST IF CORRECT

Answers

The answer is the independent variable because the independent variable will always change or affect the dependent variable.

Answer: I would say A. Dependent? Nah it’s B. Prob

Explanation: hope this helps.

Os pavões são animais orgulhosos?

Answers

Answer:

peacocks are proud animals say

Explanation:

What special abilities would it take to do a job like robert Hooke's—designing and presenting different experiments each week?

Answers

Answer:

Imagination, ingenuity and dedication

Explanation:

Imagination is "the faculty or action of forming new ideas, or images or concepts of external objects not present to the senses"(Oxford dictionary).

Ingenuity is "the quality of being clever, original, and inventive"(Oxford dictionary).

Dedication is "the quality of being dedicated or committed to a task or purpose"(Oxford dictionary).

In order to design and present a new experiment each week, the experimenter must be able to mentally create pictures that aren't already present with the senses. This is imagination and it stems from ingenuity or creativity. Then the experimenter must painstakingly work on these ideas in order to turn imagination to reality. This requires dedication.

Which muscle is highlighted below?
O A. Obliques
O B. Latissimus dorsi
O C. Biceps brachii
O D. Rectus abdominus​

Which muscle is highlighted below?O A. ObliquesO B. Latissimus dorsiO C. Biceps brachiiO D. Rectus abdominus

Answers

Answer:

C: Biceps Brachii

Explanation:

Obliques are your muscles on the side of your back that control lateral movement, latissimus dorsi are back muscles that mainly help with any motion of your back, Biceps are the muscles on your forearm, pictured in the diagram, and rectus abdominus are your abs that help with abdominal movement and helps in breathing and the compression of the abdominal viscera.

The muscle highlighted is biceps brachii.

What is muscle?"A band or bundle of fibrous tissue in a human or animal body that has the ability to contract, producing movement in or maintaining the position of parts of the body."It is of three types: skeletal muscle, smooth muscle and cardiac muscle.Skeletal muscles are striated, voluntary muscle. They connects bones, tendons and ligaments. They helps in movement.Smooth muscles are striated, involuntary muscle. They line organs and provide protection.Cardiac muscle are nonstriated, involuntary muscle present in heart.What is biceps brachii?"It is a muscle that is present on the ventral portion of the upper arm."It helps in flexes and supination of forearm.

Hence, the correct option is C. Biceps brachii.

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A father is heterozygous (AO) for his type A blood and a mother is heterozygous for her type B(BO) blood. What percentage of their offspring would you expect to have a child with O type blood?

Answers

Answer:

2 : 2 BO : OO

Explanation:

Children either have blood group B or O thus the probability of a child being either blood group B or O is 50%.

The pH indicator bromothymol blue is an alkaline solution and yellow is an acidic solution. A slight increase in acidity. Such as when co2 gas is added, causes a solution with the indicator to change from blue to yellow. A solution with the indicator would be most likely to turn from yellow to blue when which combination of factors exists?

Answers

Water plants in the solution are placed under a bright lamp. Thus, option "B" is correct.

Explain your answer briefly?

As we know adding carbon dioxide in as solution result in the change of its acidity this is result in the indicator to change from blue to yellow. In the question, it is asked that what factors from the given option will cause yellow indictor to blue which means what factors cause the solution to be alkaline from acidic.

Placing the green water plants in the solution under a bright lamp will cause the is utilizing and remove present carbon dioxide in the solution and leads the to blue color from the yellow color of the solution.

Thus, this could be the answer.

The question is incomplete, however, the missing part is given as below:

A. Yeast cells and sugar are placed in the solution. B. Water plants in the solution are placed under a bright lamp. C. Algae are placed in the solution and left in a dark room. D. A person blows air into the solution through a straw.

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Linnaeus used similarities in structure to determine relationships among organisms.


Please select the best answer from the choices provided

T
F

Answers

False fales gsgwiwiwbw

Scientists have recently modified the bacteria that cause tooth decay by inserting a fragment of DNA into the bacteria's DNA that prevents it from producing lactic acid. What is the new DNA called?
foreign DNA
restriction DNA
recombinant DNA
transgenic DNA

Answers

Scientists have recently modified the bacteria that cause tooth decay by inserting a fragment of DNA into the bacteria's DNA that prevents it from producing lactic acid. This new DNA is called recombinant DNA.

What is recombination DNA?

Genetic recombination is the exchange of genes between two DNA molecules to form new combinations of genes. Like mutation, genetic recombination contributes to the genetic diversity of a population, which is the source of evolutionary variation.

Bacteria have two mechanisms of genetic variability: mutation and gene recombination. Gene recombination occurs by three types of mechanisms: transformation, conjugation and transduction. Transformation is the incorporation of free DNA by the bacterial cell.

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Cell organelle


Holds water solutions, provides support to the
cell when full

Answers

Answer:

It is the vacuole - Holds water solutions, provides support to the cell when full

The lengths of a particular animal's pregnancies are approximately normally distributed, with mean u = 255 days and standard deviation o = 8 days. (a) What proportion of pregnancies lasts more than 269 days? (b) What proportion of pregnancies lasts between 243 and 259 days? (c) What is the probability that a randomly selected pregnancy lasts no more than 247 days? (d) A "very preterm" baby is one whose gestation period is less than 237 days. Are very preterm babies unusual? (a) The proportion of pregnancies that last more than 269 days is (Round to four decimal places as needed.) (b) The proportion of pregnancies that last between 243 and 259 days is (Round to four decimal places as needed.) than 247 ays is (c) The probability that a randomly selected pregnancy lasts no (Round to four decimal places as needed.) This event unusual because the probability is than 0.05. (d) The probability of a "very preterm" baby is (Round to four decimal places as needed.)

Answers

(a) Approximately 0.0401 or 4.01% of pregnancies last more than 269 days.

(b) Approximately 0.6247 or 62.47% of pregnancies last between 243 and 259 days.

(c) The probability is 0.1587 or 15.87%.

(d) Since this is less than 0.05, the probability of a "very preterm" baby is less than 0.05. Therefore, "very preterm" babies are considered unusual.

To solve these problems, we can use the standard normal distribution and z-scores.

(a) To find the proportion of pregnancies that last more than 269 days, we need to calculate the area under the normal curve to the right of 269. First, we calculate the z-score:

z = (269 - u) / o = (269 - 255) / 8 = 14 / 8 = 1.75

Looking up the z-score of 1.75 in the standard normal distribution table, we find that the corresponding area to the left is approximately 0.9599. Since we want the proportion to the right of 269, we subtract this value from 1:

Proportion = 1 - 0.9599 = 0.0401

Therefore, approximately 0.0401 or 4.01% of pregnancies last more than 269 days.

(b) To find the proportion of pregnancies that last between 243 and 259 days, we need to calculate the area under the normal curve between these two values. We calculate the z-scores for both values:

z1 = (243 - u) / o = (243 - 255) / 8 = -12 / 8 = -1.5

z2 = (259 - u) / o = (259 - 255) / 8 = 4 / 8 = 0.5

Using the standard normal distribution table, we find the area to the left of z1 (-1.5) is approximately 0.0668, and the area to the left of z2 (0.5) is approximately 0.6915. To find the area between these two z-scores, we subtract the smaller area from the larger area:

Proportion = 0.6915 - 0.0668 = 0.6247

Therefore, approximately 0.6247 or 62.47% of pregnancies last between 243 and 259 days.

(c) To find the probability that a randomly selected pregnancy lasts no more than 247 days, we calculate the z-score:

z = (247 - u) / o = (247 - 255) / 8 = -8 / 8 = -1

Looking up the z-score of -1 in the standard normal distribution table, we find the corresponding area to the left is approximately 0.1587. Therefore, the probability is 0.1587 or 15.87%.

(d) To determine if "very preterm" babies (gestation period less than 237 days) are unusual, we calculate the z-score:

z = (237 - u) / o = (237 - 255) / 8 = -18 / 8 = -2.25

Looking up the z-score of -2.25 in the standard normal distribution table, we find the corresponding area to the left is approximately 0.0122. Since this is less than 0.05, the probability of a "very preterm" baby is less than 0.05. Therefore, "very preterm" babies are considered unusual.

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Which of the following is true in regard to bile? The production of bile is stimulated by cholecystokinin The release of bile into the duodenum is stimulated by secretin. O It contains concentrated enzymes involved in lipid digestion. O None of these is correct

Answers

Answer: The statement "The production of bile is stimulated by cholecystokinin" is true. (Option 1)

Explanation:

Statement 1: The small intestine releases the hormone cholecystokinin (CCK) in reaction to the consumption of food, particularly fatty meals. It encourages the liver and gallbladder to produce and discharge bile. In the breakdown and absorption of lipids, bile is an essential component.

Statement 2: Another hormone produced by the small intestine, secretin's main function is to trigger the production of pancreatic juices, which are composed of water, bicarbonate ions, and digestive enzymes. The bile does not directly respond to secretin when it is released into the duodenum.

Statement 3: There are no concentrated enzymes in bile. Instead, it includes bile salts that help with the digestion and emulsification of lipids. The surface area available for the activity of lipases, which are enzymes involved in lipid digestion, is increased when giant fat globules are broken down into smaller droplets by bile salts.

Keywords: Bile, CCK, Secretin, Secretion, Digestive enzymes

What are the challenges for forensic scientists in identifying poisons?

Answers

Toxicologists sometimes have to work with relatively small sample numbers, which is one of the main difficulties they encounter. This highlights the significance of doing all tests with the utmost care and using sensitive equipment.

ChallengesWhile forensic toxicology develops and grows, there are still many difficulties that forensic toxicologists must overcome, including the introduction of new substances, variations in laboratory requirements, and differences in how toxicological results are interpreted.Whereas injection exposure through needlestick injuries is a risk in the medical industries, it is difficult for toxicology to conduct studies that accurately reflect real-world workplace settings, for which inhalation exposure and dermal exposure are most crucial.

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Only females can carry sex linked genetic disorders. Why?.

Answers

Because the X chromosome in a female is what can carry a genetic disorder
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Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties, Our ability to recognize material can make us feel _____, which might lead to poorer performance on certain tests. Who plans the layout of towns and cities, making them functional and attractive? As part of her job, Kate plans the layout of towns and cities, making them functional and attractive. Kate is an The set of multiple companies directly linked by one or more of the upstream and downstream What does the word construed suggest the author feels about the Constitution? The Constitution has more value than the rights of the individual people it governs. The Constitution is an infallible document, regardless of interpretations. The Constitution may be interpreted in a variety of ways to benefit the people. The Constitution may be interpreted in a way that would harm the people. Calculate the following: a) A point charge q is located at distance z above a grounded conducting plane. Find the net force exerted by the conducting plane on the charge. b) Calculate the induced charge density on the conducting plane. how does a person's worldview might impact the type of leadership or government they want in a society? What is five difference between VPN and SAN Help me with number 4 please thank you! What is the purpose of folic acid during pregnancy? The weight of an object can change because of the forces acting on the object. Which force causes the weight of an object to change? A tower stands on level ground. From a point P on the ground, the angle of elevation of the top of the tower is 26. Another point Q is 3m vertically above P and from this point the angle of elevation of the top of the tower is 21 . Find the height of the tower. Plan an investigation to examine how heart rate changes during and after exercise. a rectangle has a length of 6.5 M and a width of 7.3 M what is the area and the perimeter Which are the five autonomous regions of ethnic minorities in China? A monopoly is different from a perfectly competitive firm in that a monopoly:_________ There are no foods that can actually protect your body.A. TrueB. False During the 5th party system, which group did NOT support the Democratic Party? en la actualidad, aun hay pases colonizados en frica Find the best quadratic approximation, Q(x, y) of 1 5x y for (x, y) near (0,0) Q(x, y) = ___